FIGURE 2 

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Residues crucial for maintaining short paths in network communication mediate signaling in proteins

Antonio del Sol, Hirotomo Fujihashi, Dolors Amoros & Ruth Nussinov

doi:10.1038/msb4100063

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Schematic representation of the analysis for determining the conserved central positions based on an example of a protein family comprising four proteins. The position shown in red in the family structural alignment is central in the network representation of each family member. In the family member structures, this same position is represented in blue.

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