FIGURE 1
FROM:
Core transcriptional regulatory circuitry in human hepatocytes
Duncan T Odom, Robin D Dowell, Elizabeth S Jacobsen, Lena Nekludova, P Alexander Rolfe, Timothy W Danford, David K Gifford, Ernest Fraenkel, Graeme I Bell & Richard A Young
doi:10.1038/msb4100059
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(A) Transcription factor crosstalk and autoregulation in the core regulatory circuitry of human hepatocytes. Regulators are shown as black ovals, with genomic occupancy of promoter regions indicated by blue or red (for autoregulatory loops) lines. (B) Frequency of network motifs in core hepatocyte regulatory network. For clarity, only combinations potentially controlling 20 or more genes are shown for the two-, three-, and four-factor multi-input motifs. (See also Supplementary Table S2).