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The proteomes of neurotransmitter receptor complexes form modular networks with distributed functionality underlying plasticity and behaviour

Andrew J Pocklington, Mark Cumiskey, J Douglas Armstrong & Seth G N Grant

doi:10.1038/msb4100041

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A three-step strategy for analysis of synapse proteome organisation. Step 1 (Proteomics) was the collection of proteomic data identifying specific proteins. Step 2 (Annotation) was the collection of specific structural and functional data on individual proteins from Step 1, which was followed by Step 3 (Analysis) using statistical and network approaches.

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