FIGURE 4
FROM:
A global view of pleiotropy and phenotypically derived gene function in yeast
Aimée Marie Dudley, Daniel Maarten Janse, Amos Tanay, Ron Shamir & George McDonald Church
doi:10.1038/msb4100004
BACK TO ARTICLEFigure 4: A comparison of the information derived from (A) phenotypic profile data and (B) synthetic lethal data

Complex 113 (the PAF transcriptional complex) and 137 (the Sap30 histone deacetylase complex) were taken from the Gavin et al data set. Black arrows indicate genetic interactions derived from membership in the same phenotypic cluster; black boxes highlight these same interactions for members of the same complex. Blue arrows indicate synthetic lethal interactions between CDC73 and members of either complex. The figures include only the protein complex subunits that were members of a phenotype profile cluster.
