Subject archive

Synthetic biology

2009

Environment-specific combinatorial cis-regulation in synthetic promoters

Jason Gertz & Barak A Cohen

doi:10.1038/msb.2009.1
Published online: 17 February 2009

How selection affects phenotypic fluctuation

Yoichiro Ito, Hitoshi Toyota, Kunihiko Kaneko & Tetsuya Yomo

doi:10.1038/msb.2009.23
Published online: 28 April 2009

Engineering key components in a synthetic eukaryotic signal transduction pathway

Mauricio S Antunes, Kevin J Morey, Neera Tewari-Singh, Tessa A Bowen, J Jeff Smith, Colleen T Webb, Homme W Hellinga & June I Medford

doi:10.1038/msb.2009.28
Published online: 19 May 2009

Protein sequestration generates a flexible ultrasensitive response in a genetic network

Nicolas E Buchler & Frederick R Cross

doi:10.1038/msb.2009.30
Published online: 19 May 2009

Engineered single- and multi-cell chemotaxis pathways in E. coli

Shalom D Goldberg, Paige Derr, William F DeGrado & Mark Goulian

doi:10.1038/msb.2009.41
Published online: 16 June 2009

Quantifying epistatic interactions among the components constituting the protein translation system

Tomoaki Matsuura, Yasuaki Kazuta, Takuyo Aita, Jiro Adachi & Tetsuya Yomo

doi:10.1038/msb.2009.50
Published online: 18 August 2009

Control and signal processing by transcriptional interference

Antoine Buetti-Dinh, Rosemarie Ungricht, János Z Kelemen, Chetak Shetty, Prasuna Ratna & Attila Becskei

doi:10.1038/msb.2009.61
Published online: 18 August 2009

Engineering the Salmonella type III secretion system to export spider silk monomers

Daniel M Widmaier, Danielle Tullman-Ercek, Ethan A Mirsky, Rena Hill, Sridhar Govindarajan, Jeremy Minshull & Christopher A Voigt

doi:10.1038/msb.2009.62
Published online: 15 September 2009

2008

Synthetic gene brushes: a structure–function relationship

Amnon Buxboim, Shirley S Daube & Roy Bar-Ziv

doi:10.1038/msb.2008.20
Published online: 15 April 2008

A synthetic Escherichia coli predator–prey ecosystem

Frederick K Balagaddé, Hao Song, Jun Ozaki, Cynthia H Collins, Matthew Barnet, Frances H Arnold, Stephen R Quake & Lingchong You

doi:10.1038/msb.2008.24
Published online: 15 April 2008

Recursive construction of perfect DNA molecules from imperfect oligonucleotides

Gregory Linshiz, Tuval Ben Yehezkel, Shai Kaplan, Ilan Gronau, Sivan Ravid, Rivka Adar & Ehud Shapiro

doi:10.1038/msb.2008.26
Published online: 06 May 2008

An integrated cell-free metabolic platform for protein production and synthetic biology

Michael C Jewett, Kara A Calhoun, Alexei Voloshin, Jessica J Wuu & James R Swartz

doi:10.1038/msb.2008.57
Published online: 14 October 2008

Model-guided design of ligand-regulated RNAi for programmable control of gene expression

Chase L Beisel, Travis S Bayer, Kevin G Hoff & Christina D Smolke

doi:10.1038/msb.2008.62
Published online: 28 October 2008

2007

Nano-enabled synthetic biology

Mitchel J Doktycz & Michael L Simpson

doi:10.1038/msb4100165
Published online: 10 July 2007

A synthetic gene network for tuning protein degradation in Saccharomyces cerevisiae

Chris Grilly, Jesse Stricker, Wyming Lee Pang, Matthew R Bennett & Jeff Hasty

doi:10.1038/msb4100168
Published online: 31 July 2007

Single-cell zeroth-order protein degradation enhances the robustness of synthetic oscillator

Wilson W Wong, Tony Y Tsai & James C Liao

doi:10.1038/msb4100172
Published online: 31 July 2007

Environmental signal integration by a modular AND gate

J Christopher Anderson, Christopher A Voigt & Adam P Arkin

doi:10.1038/msb4100173
Published online: 14 August 2007

Accurate prediction of gene feedback circuit behavior from component properties

Nitzan Rosenfeld, Jonathan W Young, Uri Alon, Peter S Swain & Michael B Elowitz

doi:10.1038/msb4100185
Published online: 13 November 2007

Programming gene expression with combinatorial promoters

Robert Sidney Cox, III, Michael G Surette & Michael B Elowitz

doi:10.1038/msb4100187
Published online: 13 November 2007

Systems metabolic engineering of Escherichia coli for L-threonine production

Kwang Ho Lee, Jin Hwan Park, Tae Yong Kim, Hyun Uk Kim & Sang Yup Lee

doi:10.1038/msb4100196
Published online: 04 December 2007

2006

Synthetic protein–protein interaction domains created by shuffling Cys2His2 zinc-fingers

Astrid V Giesecke, Rui Fang & J Keith Joung

doi:10.1038/msb4100053
Published online: 21 March 2006

Synthetic biology: new engineering rules for an emerging discipline

Ernesto Andrianantoandro, Subhayu Basu, David K Karig & Ron Weiss

doi:10.1038/msb4100073
Published online: 16 May 2006

Noise in transcription negative feedback loops: simulation and experimental analysis

Yann Dublanche, Konstantinos Michalodimitrakis, Nico Kümmerer, Mathilde Foglierini & Luis Serrano

doi:10.1038/msb4100081
Published online: 01 August 2006

Towards synthesis of a minimal cell

Anthony C Forster & George M Church

doi:10.1038/msb4100090
Published online: 22 August 2006

Construction of an in vitro bistable circuit from synthetic transcriptional switches

Jongmin Kim, Kristin S White & Erik Winfree

doi:10.1038/msb4100099
Published online: 12 December 2006

Dynamics of single-cell gene expression

Diane Longo & Jeff Hasty

doi:10.1038/msb4100110
Published online: 28 November 2006

2005

Refactoring bacteriophage T7

Leon Y Chan, Sriram Kosuri & Drew Endy

doi:10.1038/msb4100025
Published online: 13 September 2005

Monitoring dynamics of single-cell gene expression over multiple cell cycles

Scott Cookson, Natalie Ostroff, Wyming Lee Pang, Dmitri Volfson & Jeff Hasty

doi:10.1038/msb4100032
Published online: 22 November 2005

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