FIGURE 5
FROM:
Expression of disrupted in schizophrenia 1 (DISC1) protein in the adult and developing mouse brain indicates its role in neurodevelopment
I L Schurov, E J Handford, N J Brandon and P J Whiting
BACK TO ARTICLEFigure 5.
Distribution of DISC1 expression in the developing embryonic mouse brain. (a) Lysates from the pool of whole embryonic mouse brains at different time points (E10.5–E20.5) were blotted for D27 antibody to reveal DISC1-specific bands. Lysate from adult cortex was used as a positive control. (b) The same samples were blotted for 
-tubulin. (c) Quantification of immunoblots from three independent experiments are shown as four lines representing four different DISC1 bands, (d) or were plotted as mean
SEM of band intensity (*
P<0.0175) measured using the Li-Cor Odyssey™. Two doublet bands were identified (71 and 75 kDa; 100 and 105 kDa) in all analysed samples (a). Quantitations of immunoblots demonstrated significant changes in the expression of the band 2 (100 kDa) during development with a peak at E13.5 (c, d).
