Molecular Psychiatry

FIGURE 3

FROM:

Expression of disrupted in schizophrenia 1 (DISC1) protein in the adult and developing mouse brain indicates its role in neurodevelopment

I L Schurov, E J Handford, N J Brandon and P J Whiting

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Figure 3.

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Confocal images of adult mouse brain demonstrating DISC1-ir in neurons in different brain regions. (a) Colocalization of DISC1-ir (red) with MAP 2 (green) in the cortex, (b) hippocampus, (c) anterior hypothalamus. (d) Colocalization of DISC1-ir (red) with GFAP (green) in hippocampus. DISC1 expression colocalized with MAP2 (notice yellow colour in high power images in a–c). At the same time, DISC1 and GFAP did not demonstrate any coexpression (d). Scale bars, 50 mum (a), 80 mum (b–d), and 100 mum (single labelling images in a–d).

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