Molecular Psychiatry

FIGURE 2

FROM:

Abnormalities of myelination in schizophrenia detected in vivo with MRI, and post-mortem with analysis of oligodendrocyte proteins

S W Flynn, D J Lang, A L Mackay, V Goghari, I M Vavasour, K P Whittall, G N Smith, V Arango, J J Mann, A J Dwork, P Falkai and W G Honer

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Figure 2.

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Myelin water fraction maps in healthy comparison subjects and patients with schizophrenia. These maps are for illustrative purposes only, and are created from the T2 slice as shown in Figure 1. The intensity of these images is proportional to the myelin water fraction. The first series of three myelin maps are from a 27-year-old healthy male (a), a 27-year-old male with first-episode psychosis (b), and a 25-year-old male with chronic schizophrenia (c). The second three myelin maps are from a 19-year-old healthy male (d), a 19-year-old male with first-episode psychosis (e), and a 22-year-old male with chronic schizophrenia (f).

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