TABLE OF CONTENTS

Volume 22, Issue 5 (May 2017)

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Image

Homer1b/c clustering is impaired in Phelan-McDermid Syndrome iPSCs derived neurons

C Vicidomini, L Ponzoni, D Lim, M J Schmeisser, D Reim, N Morello, D Orellana, A Tozzi, V Durante, P Scalmani, M Mantegazza, A A Genazzani, M Giustetto, M Sala, P Calabresi, T M Boeckers, C Sala and C Verpelli

Mol Psychiatry 22: 637; doi:10.1038/mp.2017.82

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News and Commentary

Biomarkers in the diagnosis of CTE

Antemortem biomarker support for a diagnosis of clinically probable chronic traumatic encephalopathy Open

M Y Pullman, D L Dickstein, S T DeKosky and S Gandy

Mol Psychiatry 22: 638-639; advance online publication, January 10, 2017; doi:10.1038/mp.2016.236

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Perspective

Epigenetic programming by stress and glucocorticoids along the human lifespan

A S Zannas and G P Chrousos

Mol Psychiatry 22: 640-646; advance online publication, March 14, 2017; doi:10.1038/mp.2017.35

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Immediate Communication

Delta-frequency stimulation of cerebellar projections can compensate for schizophrenia-related medial frontal dysfunction

K L Parker, Y C Kim, R M Kelley, A J Nessler, K-H Chen, V A Muller-Ewald, N C Andreasen and N S Narayanan

Mol Psychiatry 22: 647-655; advance online publication, March 28, 2017; doi:10.1038/mp.2017.50

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Expert Review

Identifying fast-onset antidepressants using rodent models

M J Ramaker and S C Dulawa

Mol Psychiatry 22: 656-665; advance online publication, March 21, 2017; doi:10.1038/mp.2017.36

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Review

The dopamine hypothesis of bipolar affective disorder: the state of the art and implications for treatment Open

A H Ashok, T R Marques, S Jauhar, M M Nour, G M Goodwin, A H Young and O D Howes

Mol Psychiatry 22: 666-679; advance online publication, March 14, 2017; doi:10.1038/mp.2017.16

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Original Articles

Genetic Otx2 mis-localization delays critical period plasticity across brain regions

H H C Lee, C Bernard, Z Ye, D Acampora, A Simeone, A Prochiantz, A A Di Nardo and T K Hensch

Mol Psychiatry 22: 680-688; advance online publication, February 14, 2017; doi:10.1038/mp.2017.1

Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice

C Vicidomini, L Ponzoni, D Lim, M J Schmeisser, D Reim, N Morello, D Orellana, A Tozzi, V Durante, P Scalmani, M Mantegazza, A A Genazzani, M Giustetto, M Sala, P Calabresi, T M Boeckers, C Sala and C Verpelli

Mol Psychiatry 22: 689-702; advance online publication, March 29, 2016; doi:10.1038/mp.2016.30

Prefrontal gray matter volume mediates genetic risks for obesity

N Opel, R Redlich, C Kaehler, D Grotegerd, K Dohm, W Heindel, H Kugel, A Thalamuthu, N Koutsouleris, V Arolt, A Teuber, H Wersching, B T Baune, K Berger and U Dannlowski

Mol Psychiatry 22: 703-710; advance online publication, March 28, 2017; doi:10.1038/mp.2017.51

Sphingomyelin-induced inhibition of the plasma membrane calcium ATPase causes neurodegeneration in type A Niemann–Pick disease

A Pérez-Cañamás, S Benvegnù, C B Rueda, A Rábano, J Satrústegui and M D Ledesma

Mol Psychiatry 22: 711-723; advance online publication, September 13, 2016; doi:10.1038/mp.2016.148

Heightened extended amygdala metabolism following threat characterizes the early phenotypic risk to develop anxiety-related psychopathology

A J Shackman, A S Fox, J A Oler, S E Shelton, T R Oakes, R J Davidson and N H Kalin

Mol Psychiatry 22: 724-732; advance online publication, August 30, 2016; doi:10.1038/mp.2016.132

Loss of hypothalamic corticotropin-releasing hormone markedly reduces anxiety behaviors in mice

R Zhang, M Asai, C E Mahoney, M Joachim, Y Shen, G Gunner and J A Majzoub

Mol Psychiatry 22: 733-744; advance online publication, September 6, 2016; doi:10.1038/mp.2016.136

Transglutaminase 2 overexpression induces depressive-like behavior and impaired TrkB signaling in mice

C D Pandya, N Hoda, A Crider, D Peter, A Kutiyanawalla, S Kumar, A O Ahmed, G Turecki, C M Hernandez, A V Terry Jr and A Pillai

Mol Psychiatry 22: 745-753; advance online publication, September 13, 2016; doi:10.1038/mp.2016.145

cAMP signaling in brain is decreased in unmedicated depressed patients and increased by treatment with a selective serotonin reuptake inhibitor

M Fujita, E M Richards, M J Niciu, D F Ionescu, S S Zoghbi, J Hong, S Telu, C S Hines, V W Pike, C A Zarate and R B Innis

Mol Psychiatry 22: 754-759; advance online publication, October 11, 2016; doi:10.1038/mp.2016.171

Whole-transcriptome brain expression and exon-usage profiling in major depression and suicide: evidence for altered glial, endothelial and ATPase activity

S P Pantazatos, Y-Y Huang, G B Rosoklija, A J Dwork, V Arango and J J Mann

Mol Psychiatry 22: 760-773; advance online publication, August 16, 2016; doi:10.1038/mp.2016.130

Genome-wide association study of positive emotion identifies a genetic variant and a role for microRNAs

A P Wingo, L M Almli, J S Stevens, T Jovanovic, T S Wingo, G Tharp, Y Li, A Lori, M Briscione, P Jin, E B Binder, B Bradley, G Gibson and K J Ressler

Mol Psychiatry 22: 774-783; advance online publication, September 6, 2016; doi:10.1038/mp.2016.143

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Corrigendum

Pharmacological enhancement of mGlu5 receptors rescues behavioral deficits in SHANK3 knock-out mice FREE

C Vicidomini, L Ponzoni, D Lim, M J Schmeisser, D Reim, N Morello, D Orellana, A Tozzi, V Durante, P Scalmani, M Mantegazza, A A Genazzani, M Giustetto, M Sala, P Calabresi, T M Boeckers, C Sala and C Verpelli

Mol Psychiatry 22: 784; advance online publication, April 26, 2016; doi:10.1038/mp.2016.70

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Errata

Genetic Otx2 mis-localization delays critical period plasticity across brain regions FREE

H H C Lee, C Bernard, Z Ye, D Acampora, A Simeone, A Prochiantz, A A Di Nardo and T K Hensch

Mol Psychiatry 22: 785; advance online publication, April 4, 2017; doi:10.1038/mp.2017.83

Transglutaminase 2 overexpression induces depressive-like behavior and impaired TrkB signaling in mice FREE

C D Pandya, N Hoda, A Crider, D Peter, A Kutiyanawalla, S Kumar, A O Ahmed, G Turecki, C M Hernandez, A V Terry and A Pillai

Mol Psychiatry 22: 786; advance online publication, October 25, 2016; doi:10.1038/mp.2016.199