ADVANCE ONLINE PUBLICATION

The latest research papers, published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).
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November 27 2009

Original Article

Expression of Forkhead-box protein A1, a marker of luminal A type breast cancer, parallels low Oncotype DX 21-gene recurrence scores

Foluso O Ademuyiwa, Mangesh A Thorat, Rohit K Jain, Harikrishna Nakshatri and Sunil Badve

Mod Pathol advance online publication, November 27, 2009; doi:10.1038/modpathol.2009.172

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November 20 2009

Original Articles

Flow cytometric detection of peripheral blood involvement by mycosis fungoides and Sézary syndrome using T-cell receptor Vbeta chain antibodies and its application in blood staging

Bo Feng, Jeffrey L Jorgensen, Dan Jones, Su S Chen, Ying Hu, L Jeffrey Medeiros and Sa A Wang

Mod Pathol advance online publication, November 20, 2009; doi:10.1038/modpathol.2009.175

Most primary central nervous system diffuse large B-cell lymphomas occurring in immunocompetent individuals belong to the nongerminal center subtype: a retrospective analysis of 31 cases

Eyas M Hattab, Sarah E Martin, Sohaib M Al-Khatib, William J Kupsky, Gail H Vance, Ryan A Stohler, Magdalena Czader and Mousa A Al-Abbadi

Mod Pathol advance online publication, November 20, 2009; doi:10.1038/modpathol.2009.164

The prognostic value of Ki67 is dependent on estrogen receptor status and histological grade in premenopausal patients with node-negative breast cancer

Marie Klintman, Pär-Ola Bendahl, Dorthe Grabau, Kristina Lövgren, Per Malmström and Mårten Fernö for the South Sweden Breast Cancer Group

Mod Pathol advance online publication, November 20, 2009; doi:10.1038/modpathol.2009.167

Hepatitis C-associated hepatocellular carcinomas in non-cirrhotic livers

Matthew M Yeh, Hubert Darius-J Daniel and Michael Torbenson

Mod Pathol advance online publication, November 20, 2009; doi:10.1038/modpathol.2009.174

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November 13 2009

Original Articles

Micropapillary ductal carcinoma in situ of the breast: an inter-institutional study

Isabella Castellano, Caterina Marchiò, Mariano Tomatis, Antonio Ponti, Denise Casella, Simonetta Bianchi, Vania Vezzosi, Riccardo Arisio, Francesca Pietribiasi, Alfonso Frigerio, Maria Piera Mano, Umberto Ricardi, Elena Allia, Valeria Accortanzo, Antonio Durando, Giovanni Bussolati, Tibor Tot and Anna Sapino

Mod Pathol advance online publication, November 13, 2009; doi:10.1038/modpathol.2009.169

Upregulation of vimentin and aberrant expression of E-cadherin/beta-catenin complex in oral squamous cell carcinomas: correlation with the clinicopathological features and patient outcome

Lai-Kui Liu, Xiao-Yun Jiang, Xiang-Xiang Zhou, Dong-Miao Wang, Xiao-Ling Song and Hong-Bing Jiang

Mod Pathol advance online publication, November 13, 2009; doi:10.1038/modpathol.2009.160

Hepatic pseudolymphoma: a clinicopathological study of five cases and review of the literature

Yoh Zen, Takahiko Fujii and Yasuni Nakanuma

Mod Pathol advance online publication, November 13, 2009; doi:10.1038/modpathol.2009.165

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November 6 2009

Original Articles

Coincident expression of beta-catenin and cyclin D1 in endometrial stromal tumors and related high-grade sarcomas

Shuichi Kurihara, Yoshinao Oda, Yoshihiro Ohishi, Eisuke Kaneki, Hiroaki Kobayashi, Norio Wake and Masazumi Tsuneyoshi

Mod Pathol advance online publication, November 6, 2009; doi:10.1038/modpathol.2009.162

AID protein expression in chronic lymphocytic leukemia/small lymphocytic lymphoma is associated with poor prognosis and complex genetic alterations

Mona Leuenberger, Simona Frigerio, Peter J Wild, Franziska Noetzli, Dimitri Korol, Dieter R Zimmermann, Carole Gengler, Nicole M Probst-Hensch, Holger Moch and Marianne Tinguely

Mod Pathol advance online publication, November 6, 2009; doi:10.1038/modpathol.2009.156

Estrogen receptor-beta expression in invasive breast cancer in relation to molecular phenotype: results from the Nurses' Health Study

Jonathan D Marotti, Laura C Collins, Rong Hu and Rulla M Tamimi

Mod Pathol advance online publication, November 6, 2009; doi:10.1038/modpathol.2009.158

Androgen receptor in breast cancer: expression in estrogen receptor-positive tumors and in estrogen receptor-negative tumors with apocrine differentiation

Leo A Niemeier, David J Dabbs, Sushil Beriwal, Joan M Striebel and Rohit Bhargava

Mod Pathol advance online publication, November 6, 2009; doi:10.1038/modpathol.2009.159

High prevalence of PIK3CA/AKT pathway mutations in papillary neoplasms of the breast

Megan L Troxell, Judith Levine, Carol Beadling, Andrea Warrick, Jennifer Dunlap, Ajia Presnell, Janice Patterson, Arielle Shukla, Neal R Olson, Michael C Heinrich and Christopher L Corless

Mod Pathol advance online publication, November 6, 2009; doi:10.1038/modpathol.2009.142

Cadherin expression in gastrointestinal tract endometriosis: possible role in deep tissue invasion and development of malignancy

Katy Van Patten, Vinita Parkash and Dhanpat Jain

Mod Pathol advance online publication, November 6, 2009; doi:10.1038/modpathol.2009.127

Cytoskeleton alterations in melanoma: aberrant expression of cortactin, an actin-binding adapter protein, correlates with melanocytic tumor progression

Xu-Zhi Xu, Marileila Varella Garcia, Tian-yu Li, Li-Yan Khor, R Sujatha Gajapathy, Cindy Spittle, Scott Weed, Stuart R Lessin and Hong Wu

Mod Pathol advance online publication, November 6, 2009; doi:10.1038/modpathol.2009.157

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October 23 2009

Original Articles

Expression of gastric pyloric mucin, MUC6, in colorectal serrated polyps

Angela N Bartley, Patricia A Thompson, Julie A Buckmeier, Carole Y Kepler, Chiu-Hsieh Hsu, Manuel S Snyder, Peter Lance, Achyut Bhattacharyya and Stanley R Hamilton

Mod Pathol advance online publication, October 23, 2009; doi:10.1038/modpathol.2009.155

Clinicopathological predictors of EGFR/KRAS mutational status in primary lung adenocarcinomas

Sanja Dacic, Yongli Shuai, Samuel Yousem, Paul Ohori and Marina Nikiforova

Mod Pathol advance online publication, October 23, 2009; doi:10.1038/modpathol.2009.154

p53 overexpression in morphologically ambiguous endometrial carcinomas correlates with adverse clinical outcomes

Karuna Garg, Mario M Leitao Jr, Christine A Wynveen, Gabriel L Sica, Jinru Shia, Weiji Shi and Robert A Soslow

Mod Pathol advance online publication, October 23, 2009; doi:10.1038/modpathol.2009.153

Triple-negative breast cancer: clinicopathological characteristics and relationship with basal-like breast cancer

Aye Aye Thike, Poh Yian Cheok, Ana Richelia Jara-Lazaro, Benita Tan, Patrick Tan and Puay Hoon Tan

Mod Pathol advance online publication, October 23, 2009; doi:10.1038/modpathol.2009.145

Collagenous sprue is not always associated with dismal outcomes: a clinicopathological study of 19 patients

Efsevia Vakiani, Carolina Arguelles-Grande, Mahesh M Mansukhani, Suzanne K Lewis, Heidrun Rotterdam, Peter H Green and Govind Bhagat

Mod Pathol advance online publication, October 23, 2009; doi:10.1038/modpathol.2009.151

Quantitative evaluation of CpG island methylation in hyperplastic polyps

Cecily P Vaughn, Andrew R Wilson and Wade S Samowitz

Mod Pathol advance online publication, October 23, 2009; doi:10.1038/modpathol.2009.150

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October 16 2009

Original Articles

Follicular lymphomas with plasmacytic differentiation include two subtypes

Joel F Gradowski, Elaine S Jaffe, Roger A Warnke, Stefania Pittaluga, Urvashi Surti, Leena A Gole and Steven H Swerdlow

Mod Pathol advance online publication, October 16, 2009; doi:10.1038/modpathol.2009.146

Grading of gastric foveolar-type dysplasia in Barrett's esophagus

Dipti Mahajan, Ana E Bennett, Xiaobo Liu, James Bena and Mary P Bronner

Mod Pathol advance online publication, October 16, 2009; doi:10.1038/modpathol.2009.147

Patterns of GRP78 and MTJ1 expression in primary cutaneous malignant melanoma

John A Papalas, Robin T Vollmer, Mario Gonzalez-Gronow, Salvatore V Pizzo, James Burchette, Kenneth E Youens, Krystal B Johnson and Maria A Selim

Mod Pathol advance online publication, October 16, 2009; doi:10.1038/modpathol.2009.152

Human papillomavirus genotypes in anal intraepithelial neoplasia and anal carcinoma as detected in tissue biopsies

Anna K Wong, Raymond C Chan, Nidhi Aggarwal, Manoj K Singh, W Stephen Nichols and Shikha Bose

Mod Pathol advance online publication, October 16, 2009; doi:10.1038/modpathol.2009.143

Lactate dehydrogenase 5 expression in melanoma increases with disease progression and is associated with expression of Bcl-XL and Mcl-1, but not Bcl-2 proteins

Liqing Zhuang, Richard A Scolyer, Rajmohan Murali, Stanley W McCarthy, Xu Dong Zhang, John F Thompson and Peter Hersey

Mod Pathol advance online publication, October 16, 2009; doi:10.1038/modpathol.2009.129

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October 9 2009

Original Articles

Carboxypeptidase M: a biomarker for the discrimination of well-differentiated liposarcoma from lipoma

Michele R Erickson-Johnson, Amber R Seys, Christopher W Roth, Allison A King, Rachael L Hulshizer, Xiaoke Wang, Yan W Asmann, Ricardo V Lloyd, Eapen K Jacob and Andre M Oliveira

Mod Pathol advance online publication, October 9, 2009; doi:10.1038/modpathol.2009.149

HMGA1 correlates with advanced tumor grade and decreased survival in pancreatic ductal adenocarcinoma

Alexandra C Hristov, Leslie Cope, Francescopaolo Di Cello, Marcelo Delos Reyes, Mansher Singh, Joelle A Hillion, Amy Belton, Biju Joseph, Andrew Schuldenfrei, Christine A Iacobuzio-Donahue, Anirban Maitra and Linda MS Resar

Mod Pathol advance online publication, October 9, 2009; doi:10.1038/modpathol.2009.139

Diagnostic utility of SALL4 in primary germ cell tumors of the central nervous system: a study of 77 cases

Kaiyong Mei, Aijun Liu, Robert W Allan, Peng Wang, Zhaoli Lane, Ty W Abel, Lixin Wei, Hong Cheng, Shuangping Guo, Yan Peng, Dinesh Rakheja, Min Wang, Joe Ma, Maria M Rodriguez, Jianping Li and Dengfeng Cao

Mod Pathol advance online publication, October 9, 2009; doi:10.1038/modpathol.2009.148

CDX2 expression in the intestinal-type gastric epithelial neoplasia: frequency and significance

Do Youn Park, Amitabh Srivastava, Gwang Ha Kim, Mari Mino-Kenudson, Vikram Deshpande, Lawrence R Zukerberg, Geum Am Song and Gregory Y Lauwers

Mod Pathol advance online publication, October 9, 2009; doi:10.1038/modpathol.2009.135

Low membranous expression of beta-catenin and high mitotic count predict poor prognosis in endometrioid carcinoma of the ovary

Daniel G Rosen, Zhihong Zhang, Bin Chang, Xuemei Wang, E Lin and Jinsong Liu

Mod Pathol advance online publication, October 9, 2009; doi:10.1038/modpathol.2009.141

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October 2 2009

Original Articles

Nuclear expression of sox11 is highly associated with mantle cell lymphoma but is independent of t(11;14)(q13;q32) in non-mantle cell B-cell neoplasms

Yi-Hua Chen, Juehua Gao, Guang Fan and LoAnn C Peterson

Mod Pathol advance online publication, October 2, 2009; doi:10.1038/modpathol.2009.140

Prognostic significance of histopathological tumor regression after neoadjuvant chemotherapy in esophageal adenocarcinomas

Rupert Langer, Katja Ott, Marcus Feith, Florian Lordick, Jörg-Rüdiger Siewert and Karen Becker

Mod Pathol advance online publication, October 2, 2009; doi:10.1038/modpathol.2009.123

Cutting a sentinel lymph node into slices is the optimal first step for examination of sentinel lymph nodes in melanoma patients

Christina Mitteldorf, Hans P Bertsch, Antonia Zapf, Christine Neumann and Lutz Kretschmer

Mod Pathol advance online publication, October 2, 2009; doi:10.1038/modpathol.2009.137

Utility of FISH in the diagnosis of angiomatoid fibrous histiocytoma: a series of 18 cases

Munir R Tanas, Brian P Rubin, Elizabeth A Montgomery, Sondra L Turner, James R Cook, Raymond R Tubbs, Steven D Billings and John R Goldblum

Mod Pathol advance online publication, October 2, 2009; doi:10.1038/modpathol.2009.138

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September 18 2009

Original Articles

Immunomodulator agent-related lymphoproliferative disorders

Robert P Hasserjian, Steve Chen, Sherrie L Perkins, Laurence de Leval, Marsha C Kinney, Todd S Barry, Jonathan Said, Megan S Lim, William G Finn, L Jeffrey Medeiros, Nancy L Harris and Dennis P O'Malley

Mod Pathol advance online publication, September 18, 2009; doi:10.1038/modpathol.2009.131

Simultaneous detection of TOP2A and HER2 gene amplification by multiplex ligation-dependent probe amplification in breast cancer

Cathy B Moelans, Roel A de Weger, Marja TM van Blokland, Elsken van der Wall and Paul J van Diest

Mod Pathol advance online publication, September 18, 2009; doi:10.1038/modpathol.2009.136

Comparative analysis of annexin-1 in neuroepithelial tumors shows altered expression with the grade of malignancy but is not associated with survival

Jens Schittenhelm, Katrin Trautmann, Ghazaleh Tabatabai, Caroline Hermann, Richard Meyermann and Rudi Beschorner

Mod Pathol advance online publication, September 18, 2009; doi:10.1038/modpathol.2009.132

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September 11 2009

Original Articles

Heparanase expression by Barrett's epithelium and during esophageal carcinoma progression

Rita Brun, Inna Naroditsky, Matti Waterman, Ofer Ben-Izhak, Gabriel Groisman, Neta Ilan and Israel Vlodavsky

Mod Pathol advance online publication, September 11, 2009; doi:10.1038/modpathol.2009.115

Clinicopathological significance of the CRTC3–MAML2 fusion transcript in mucoepidermoid carcinoma

Takahisa Nakayama, Satoru Miyabe, Mitsukuni Okabe, Hidenori Sakuma, Kei Ijichi, Yasuhisa Hasegawa, Hitoshi Nagatsuka, Kazuo Shimozato and Hiroshi Inagaki

Mod Pathol advance online publication, September 11, 2009; doi:10.1038/modpathol.2009.126

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September 4 2009

Original Articles

Anti-phosphorylated histone H3 expression in Barrett's esophagus, low-grade dysplasia, high-grade dysplasia, and adenocarcinoma

Mahmoud Goodarzi, Arlene M Correa, Jaffer A Ajani, Stephen G Swisher, Wayne L Hofstetter, Sushovan Guha, Michael T Deavers, Asif Rashid and Dipen M Maru

Mod Pathol advance online publication, September 4, 2009; doi:10.1038/modpathol.2009.133

MGMT methylation is associated primarily with the germline C>T SNP (rs16906252) in colorectal cancer and normal colonic mucosa

Nicholas J Hawkins, James H-F Lee, Justin J-L Wong, Chau-To Kwok, Robyn L Ward and Megan P Hitchins

Mod Pathol advance online publication, September 4, 2009; doi:10.1038/modpathol.2009.130

Nuclear expression of the RNA-binding protein RBM3 is associated with an improved clinical outcome in breast cancer

Annika Jögi, Donal J Brennan, Lisa Rydén, Kristina Magnusson, Mårten Fernö, Olle Stål, Signe Borgquist, Mathias Uhlen, Göran Landberg, Sven Påhlman, Fredrik Pontén and Karin Jirström

Mod Pathol advance online publication, September 4, 2009; doi:10.1038/modpathol.2009.124

A panel of antibodies to determine site of origin and malignancy in smooth muscle tumors

Cheng-Han Lee, Dmitry A Turbin, Y-C Vanessa Sung, Inigo Espinosa, Kelli Montgomery, Matt van de Rijn and C Blake Gilks

Mod Pathol advance online publication, September 4, 2009; doi:10.1038/modpathol.2009.122

Diagnostic utility of IMP3 in segregating metastatic melanoma from benign nevi in lymph nodes

Mark J Mentrikoski, Linglei Ma, Jennifer G Pryor, Loralee A McMahon, Qi Yang, Betsy O Spaulding, Glynis A Scott, Hanlin L Wang and Haodong Xu

Mod Pathol advance online publication, September 4, 2009; doi:10.1038/modpathol.2009.128

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