Modern Pathology

FIGURE 16

FROM:

Staging and reporting of urothelial carcinoma of the urinary bladder

Liang Cheng, Rodolfo Montironi, Darrell D Davidson and Antonio Lopez-Beltran

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Figure 16.

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Urothelial carcinoma invading into prostatic stroma (pT4a urothelial carcinoma). (a) Urothelial carcinoma often elicits a strong inflammatory response, unusual for prostatic adenocarcinoma. (b) Tumor cells invading prostatic stroma are usually highly pleomorphic. (c and d) Immunostaining for high molecular weight cytokeratins is diffusely and strongly positive in urothelial carcinoma. The basal cells in the adjacent prostatic glands show positive stainings for high molecular weight cytokeratin (c).

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