TABLE 1
FROM:
Primary cutaneous CD4-positive small/medium-sized pleomorphic T-cell lymphoma: a clonal T-cell lymphoproliferative disorder with indolent behavior
Karen L Grogg, Sungmi Jung, Lori A Erickson, Rebecca F McClure and Ahmet Dogan
BACK TO ARTICLETable 1. Clinicopathologic features in 15 patients with primary cutaneous CD4-positive small/medium sized pleomorphic T-cell lymphoma
| Age/sex | Site (size in cm) | Clinical impression | Phenotypic aberrancy in CD3, CD4+ T cells by IHC | Clonal TCR rearrangements | Management | Relapse | Length of follow-up (months) | |
|---|---|---|---|---|---|---|---|---|
| 1 | 55/M | Forehead (2.5) | Firm nodule 2 months | Dim/absent CD7 | PCR/Southern blot | Radiation therapy | None | 11 |
| 2 | 57/M | Behind ear (1) | Nodule | PCR | Excision | None | 9 | |
| 3 | 74/F | Eyebrow (1) | Rapid growth 2 weeks | PCR | Excision/ Radiation therapy | None | 17 | |
| 4 | 52/F | Jawline (1) | Wax/wane 6 weeks; indurated nodule; furuncle | PCR/Southern blot | None (spontaneous resolution) | None | 24 | |
| 5 | 60/F | Base of neck (NA) | Nodule | PCR | NA | NA | NA | |
| 6 | 71/M | Chin (1) | NA | PCR | NA | NA | NA | |
| 7 | 68/M | Scalp (NA) | Cyst | PCR | Excision | None | 6 | |
| 8 | 41/M | Forehead (1.5) | NA | Dim CD2 | PCR | Excision | Local recurrence at 2 months | 4 |
| 9 | 70/F | Nose (1.3) | Ulcerated nodule | PCR | NA | NA | NA | |
| 10 | 14/M | Upper arm (NA) | Cyst | Absent CD7 | PCR | Radiation therapy | None | 10 |
| 11 | 60/F | Forearm (14), back | Painful expanding lesion 1year, similar lesions on trunk | Absent CD2 | PCR/Southern blot 2 sites | Systemic chemotherapy, autologous stem cell transplant | Progression of multifocal cutaneous disease despite therapy | 26 |
| 12 | 54/M | Shoulder (1.5) | Growth 1 month; dermatofibroma | PCR | Excision | None | 1 | |
| 13 | 52/F | Axilla (1) | Nodule 1 month | Dim CD7 | PCR | Radiation therapy | None | 9 |
| 14 | 41/F | Upper arm (2) | Wax/wane 6 months; infected cyst | PCR/Southern blot | Excision | None | 4 | |
| 15 | 66/F | Back (1.5) | NA | PCR | NA | NA | NA |
NA, not available.

2 months