Modern Pathology

TABLE 3

FROM:

Clinical importance of HER2 immunohistologic heterogeneous expression in core-needle biopsies vs resection specimens for equivocal (immunohistochemical score 2+) cases

Mamatha Chivukula, Rohit Bhargava, Adam Brufsky, Urvashi Surti and David J Dabbs

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Table 3. Expression of HER2 in RS based on the FISH results of the corresponding CNB

HER2 score Amplified (Amp) group (n-18) Nonamplified (Nonamp) group (n-19)
Negative (0 or 1+)11% (2/18)42% (8/19)
Equivocal (2+)28% (5/18)37% (7/19)
Strongly positive (3+)56% (11/18)0% (0/19)
Heterogeneous (1+, 2+, 3+)5.6% (1/18)11% (4/19)
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