Modern Pathology

FIGURE 4

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Stratified epithelium in prostatic adenocarcinoma: a mimic of high-grade prostatic intraepithelial neoplasia

Omar Hameed and Peter A Humphrey

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Figure 4.

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A case (no. 4) of prostatic adenocarcinoma, where the malignant glands are not crowded and appear dispersed in the prostatic stroma (a). The glands show prominent epithelial stratification as well as elongated nuclei (b, c). A p63/AMACR antibody cocktail immunostain (d) confirms lack of basal cells and shows only focal and minimal granular cytoplasmic staining which would be considered insufficient for AMACR positivity.

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