Modern Pathology

FIGURE 12

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Renal lymphatics, and lymphatic involvement in sinus vein invasive (pT3b) clear cell renal cell carcinoma: a study of 40 cases

Stephen M Bonsib

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Figure 12.

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(a) The media of this muscular sinus vein (V) contains a tumor filled lymphatic. Immunoperoxidase stain for smooth muscle actin (red) and CD 31 (black). (b) Same nest of tumor shown in 12A. Podoplanin stain confirms intralymphatic tumor within the media of a muscular vein. Podoplanin immunoperoxidase stain.

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