Modern Pathology

FIGURE 4

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Estrogen receptor-bold italic beta is expressed in stromal cells of fibroadenoma and phyllodes tumors of the breast

Anna Sapino, Martino Bosco, Paola Cassoni, Isabella Castellano, Riccardo Arisio, Gábor Cserni, Angelo P Dei Tos, Nicoletta Fortunati, Maria G Catalano and Gianni Bussolati

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Figure 4.

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Smooth muscle differentiation of stromal cells. (a) Double immunostaining of a cellular fibroadenoma; ER-beta (brown nuclei) and smooth muscle actin (black cytoplasm) are coexpressed by stromal cells. (b) Benign phyllodes tumor; smooth muscle actin immunostaining. (c) Primary malignant phyllodes tumor and (d) its metastasis; calponin immunostaining.

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