Modern Pathology

FIGURE 2

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Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma

Chad A Livasy, Gamze Karaca, Rita Nanda, Maria S Tretiakova, Olufunmilayo I Olopade, Dominic T Moore and Charles M Perou

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Figure 2.

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Immunophenotype of basal-like carcinomas. (a) SMA and (b) p63 positivity was present in a minority of tumors, with immunoreactivity being detected in only a small percentage of tumor cells. (c) Most tumors showed strong luminal cytokeratin 8/18 expression throughout the tumor. (e) Vimentin positivity was characterized by strong and diffuse immunoreactivity. Original magnification times 400.

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