Modern Pathology

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Nuclear galectin-3 expression is an independent predictive factor of recurrence for adenocarcinoma and squamous cell carcinoma of the lung

Anne Mathieu, Isabelle Saal, Aline Vuckovic, Valérie Ransy, Pierre Vereerstraten, Herbert Kaltner, Hans-Joachim Gabius, Robert Kiss, Christine Decaestecker, Isabelle Salmon and Myriam Remmelink

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Figure 1.

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Pattern of galectin-3 expression in squamous cell carcinomas and adenocarcinomas. (a) Illustration of the weak to moderate staining in the cytoplasm of a squamous cell carcinoma. (b) An increased expression is observed in the well-differentiated areas, particularly in the keratin pearls of a squamous cell carcinoma. A solid (c) and an acinar (d) adenocarcinoma, both of which show diffuse and strong cytoplasmic and nuclear staining.

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