TABLE 2
FROM:
Comparison of genetic alterations in neuroendocrine tumors: frequent loss of chromosome 18 in ileal carcinoid tumors
Gordon G Wang, James C Yao, Samidha Worah, Jill A White, Rene Luna, Tsung-Teh Wu, Stanley R Hamilton and Asif Rashid
BACK TO ARTICLETable 2. Summary of loss of heterozygosity of chromosomes 11q, 16q and 18, and BRAF mutations in pancreatic endocrine tumors, nonileal carcinoid tumors and ileal carcinoid tumors
| Alteration | Pancreatic endocrine tumors (n=16) | Non-ileal carcinoid tumors (n=15) | Ileal carcinoid tumors (n=16) | P-value a |
|---|---|---|---|---|
| Loss of chromosome 11q | 38 (6) | 13 (2) | 13 (2) | NSb |
| Loss of chromosome 16q | 19 (3) | 0 (0) | 19 (3) | NS |
| Loss of chromosome 18, any loss | 6 (1) | 13 (2) | 69 (11) | 0.001c |
| Loss of chromosome 18, complete loss | 0 (0) | 0 (0) | 69 (11) | 0.001c |
| BRAF mutations | 0 (0) | 0 (0) | 0 (0) | NS |
Values are expressed as percent and numbers in parentheses.
a Comparison among all three groups.
b Not significant, NS.
c Pancreatic endocrine tumors vs carcinoid tumors, P=0.01 for any loss of chromosome 18, and P=0.006 for complete loss of chromosome 18.
