Modern Pathology

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Melanocytic lesions associated with dermatofibromas: a spectrum of lesions ranging from junctional nevus to malignant melanoma in situ

Roy King, Paul B Googe, Robert N Page and Martin C Mihm Jr

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Figure 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact help@nature.com or the author

Figure 1.

Compound nevus with underlying dermatofibroma.

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Figure 2.

Dermal nevus with adjacent fibrohistiocytic proliferation (a). Mart-1 highlights the melanocytic proliferation (b), whereas Factor XIIIa highlights the fibrohistiocytic proliferation (c).

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Figure 3.

Malignant melanoma in situ with the fibrohistiocytic proliferation extending up to the epidermis (a). Mart-1 stains melanoma cells in the epidermis but not the dermal proliferation (b), whereas Factor XIIIa has a reverse staining pattern highlighting the fibrohistiocytic proliferation, but not staining the melanocytic proliferation (c).

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