Modern Pathology

FIGURE 2

FROM:

Fluorescence in situ hybridization investigation of cutaneous lesions in acute promyelocytic leukemia

Joanna E Wrede, Uma Sundram, Sabine Kohler, Athena M Cherry, Daniel A Arber and Tracy I George

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Figure 2.

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(a) Representative nuclei from reactive tonsil hybridized with dual color, dual fusion PML / RARA translocation probe. Two separate red and green signals indicate lack of rearrangement of chromosomes 15q32 and 17q12 (b). Representative nuclei from the positive skin control hybridized with dual color, dual fusion PML / RARA translocation probe. A positive FISH signal pattern (1R1G2F) is illustrated.

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