TABLE 1
FROM:
Galectin-3, fibronectin-1, CITED-1, HBME1 and cytokeratin-19 immunohistochemistry is useful for the differential diagnosis of thyroid tumors
Manju L Prasad, Natalia S Pellegata, Ying Huang, Haikady N Nagaraja, Albert de la Chapelle and Richard T Kloos
BACK TO ARTICLETable 1. Protein expression in thyroid
| Diagnosis | GAL3 | FN1 | CITED1 | HBME1 | CK19 | Coexpression a |
|---|---|---|---|---|---|---|
| Carcinoma | ||||||
| Papillary (n=67) | 63 (94%) | 61 (91%) | 58 (87%) | 57 (85%) | 48 (72%) | 65 (97%) |
| Follicular (n=6) | 4 (66%) | 3 (50%) | 3 (50%) | 3 (50%) | 3 (50%) | 5 (83%) |
| Hürthle cell (n=8) | 7 (88%) | 6 (75%) | 2 (25%) | 1 (13%) | 4 (50%) | 7 (88%) |
| Anaplastic (n=4) | 4 (100%) | 4 (100%) | 0 (0%) | 0 (0%) | 1 (25%) | 4 (100%) |
| Neoplasms of undetermined malignant potential (n=7) | 6 (86%) | 1 (14%) | 3 (43%) | 2 (29%) | 1 (14%) | 3 (43%) |
| Adenoma (n=21) | 2 (10%) | 1 (5%) | 2 (10%) | 2 (10%) | 1 (5%) | 1 (5%) |
| Non-neoplastic thyroid | ||||||
| Nodular goiter (n=29) | 16 (55%) | 2 (7%) | 7 (24%) | 1 (3%) | 9 (31%) | 11 (38%) |
| Thyrotoxic hyperplasia (n=14) | 1 (7%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) |
| Normal (n=59) | 0 (0%) | 0 (0%) | 0 (0%) | 0 (0%) | 4 (7%) | 0 (0%) |
GAL3 and/or FN1 and/or HBME1: 85/85 carcinoma and 5/21 adenoma.
a Coexpression of 
2 proteins.