TABLE 1
FROM:
Overexpression of caspase-3 in hepatocellular carcinomas
Rajendra Persad, Chen Liu, Tsung-Teh Wu, Patrick S Houlihan, Stanley R Hamilton, Anna M Diehl and Asif Rashid
BACK TO ARTICLETable 1. Caspase-3 overexpression status in HCCs compared to patient and tumor characteristics
| Characteristic | Total | Caspase-3 Overexpression | P-value | |
|---|---|---|---|---|
| (n=47) | Absent (n=20) | Present (n=27) | ||
| # | % (#) | % (#) | ||
Age (years) s.d. | 61.6 13.4 | 64.3 12.6 | 59.6 13.8 | NSa |
| Gender | ||||
| Female | 19 | 37 (7) | 63 (12) | NS |
| Male | 28 | 46 (13) | 54 (15) | |
-fetoprotein
| ||||
| <40 | 12 | 58 (7) | 42 (5) | 0.01b |
| >40 | 19 | 16 (3) | 84 (16) | |
| Not available | 16 | 63 (10) | 37 (6) | |
| Hepatitis | ||||
| Absent | 25 | 44 (11) | 56 (14) | NS |
| Present | 22 | 41 (9)c | 59 (13)d | |
| Cirrhosis | ||||
| Absent | 24 | 37 (9) | 63 (15) | NS |
| Present | 23 | 48 (11) | 52 (12) | |
| Tumor stage | ||||
| 2 | 16 | 37 (6) | 63 (10) | NS |
| 3 | 17 | 47 (8) | 53 (9) | |
| 4 | 14 | 43 (6) | 57 (8) | |
| Vital status | ||||
| Alive | 20 | 45 (9) | 55 (11) | NS |
| Dead | 27 | 41 (11) | 59 (16) | |
Follow-up (months) s.d. | 29.0 29.1 | 35.1 32.4 | 24.6 26.0 | NSe |
a NS, not significant.
b
-fetoprotein <40 vs >40.
c Hepatitis B viral infection (n=3), hepatitis C viral infection (n=2), alcoholic liver disease (n=4), and hepatitis B viral infection and alcoholic liver disease (n=1).
d Hepatitis B viral infection (n=5), hepatitis C viral infection (n=5), alcoholic liver disease (n=3).
e By Kaplan and Meier method, log-rank statistic.

s.d.
-fetoprotein