Modern Pathology - FIGURE 1 for article: Embolized Crospovidone (poly[lsqb]N-vinyl-2-pyrrolidone[rsqb]) in the Lungs of Intravenous Drug Users

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Embolized Crospovidone (poly[N-vinyl-2-pyrrolidone]) in the Lungs of Intravenous Drug Users

Santhi Ganesan, Joseph Felo, Mario Saldana, Victor F Kalasinsky, Michael R Lewin-Smith and Joseph F Tomashefski Jr

FIGURE 1.

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Left upper, embolized crospovidone appears as deeply basophilic coral-like particles associated with a foreign body giant cell reaction. The vascular lumen has been greatly restricted (H&E; original magnification, 160 $times$ ). Right upper, crospovidone (deep red) in a recanalized thromboembolus (mucicarmine; original magnification, 400 $times$ ). Left lower, intravascular crospovidone (yellow-orange particles) associated with recent thrombus, in muscular pulmonary artery (Movat pentachrome; original magnification, 250 $times$ ). Right lower, crospovidone (blue-green particles) and associated foreign body granuloma have partially destroyed the vascular elastica of a non-muscular pulmonary artery (Movat pentachrome; original magnification, 250 $times$ ).

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