Modern Pathology

FIGURE 1

FROM:

Role of the DPC4 Tumor Suppressor Gene in Adenocarcinoma of the Ampulla of Vater: Analysis of 140 Cases

Denis M McCarthy, Ralph H Hruban, Pedram Argani, James R Howe, Kevin C Conlon, Murray F Brennan, Marianna Zahurak, Robb E Wilentz, John L Cameron, Charles J Yeo, Scott E Kern and David S Klimstra

BACK TO ARTICLE

FIGURE 1.

Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact help@nature.com or the author

Infiltrating ampullary adenocarcinoma and associated adenomas with high-grade dysplasia. A, infiltrating intestinal-type ampullary adenocarcinoma with negative Dpc4 labeling and adjacent stroma showing normal Dpc4 labeling. B, infiltrating pancreaticobiliary ampullary adenocarcinoma with negative Dpc4 labeling and adjacent normal duodenal crypts. C, infiltrating colloid-type adenocarcinoma with strong Dpc4 labeling. D, adenoma with high-grade dysplasia labeling for Dpc4 (arrow) with distinct Dpc4-positive (right side) and Dpc4-negative (left side) infiltrating carcinoma.

BACK TO ARTICLE