Modern Pathology

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VCAM (CD-106) and ICAM (CD-54) Adhesion Molecules Distinguish Keratoacanthomas from Cutaneous Squamous Cell Carcinomas

Nicole D Melendez, Bruce R Smoller and Michael Morgan

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FIGURE 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact help@nature.com or the author

FIGURE 1.

Fully developed keratocanthoma consisting of large irregular infiltrating squamous nests and islands (40 times).

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FIGURE 2.

Resolving keratocanthoma with scalloped epithelial remnants punctuated by perforating strands of elastin fibers (100 times).

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FIGURE 3.

Keratocanthoma temporal expression pattern for CD-54 and CD-106.

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FIGURE 4.

CD-54 immunostaining of well-developed keratocanthoma (400 times).

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FIGURE 5.

CD-106 immunostaining of well-differentiated squamous cell carcinoma (400 times).

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FIGURE 6.

CD-54 immunostaining of poorly differentiated squamous cell carcinoma (100 times).

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