TABLE 1
FROM:
Kupffer Cell Aggregation and Perivenular Distribution in Steatohepatitis
Jay H Lefkowitch, Jennifer H Haythe and Nicole Regent
BACK TO ARTICLETABLE 1. Grading and Distribution of Immune Cells in Steatohepatitis
| Case | Sex | Age (y) | ASH/NASH (Risk)b | Distributiona | ||
|---|---|---|---|---|---|---|
| CD3 | CD20 | CD68 | ||||
| 1 | F | 31 | NASH | 2+ (V) | R (V) | Agg (V) |
| (Ob) | 2+ (P) | |||||
| 2 | M | 51 | NASH | 1+ (V) | R (V) | Agg (V) |
| (Ob) | 1+ (P) | |||||
| 3 | M | 63 | NASH | 3+ (V) | R (P) | Agg (V) |
| (Ob)a | 3+ (P) | |||||
| 4 | F | 55 | NASH | 2+ (V) | R (V) | Agg (V) |
| (Ob) | 1+ (P) | |||||
| 5 | F | 39 | ASH | 1+ (V) | O | Agg (V) |
| R (P) | ||||||
| 6 | M | 51 | NASH | 1+ (V) | R (P) | Agg (V) |
| (D) | 2+ (P) | |||||
| 7 | F | 59 | ASH | 2+ (V) | R (V) | Agg (V) |
| 2+ (P) | ||||||
| 8 | F | 35 | ASH | 2+ (L) | O | Agg (V) |
| 2+ (SE) | ||||||
| 9 | M | 64 | ASH | 1+ (L) | 1+ (SE) | Agg (V) |
| 2+ (SE) | ||||||
| 10 | F | 76 | NASH | 2+ (V) | R (P + V) | Agg (V) |
| (Ob) | 1+ (P) | |||||
| 11 | M | 71 | ASH | 2+ (V) | 1+ (V) | Agg (V) |
| 3+ (P) | 1+ (P) | |||||
ASH, alcoholic steatohepatitis; NASH, nonalcoholic steatohepatitis.
a Lobular distribution of immune cells includes V (perivenular), P (portal tract), L (lobular sinusoids), and SE (within fibrous septa). Agg, aggregates.
b NASH risk factors include obesity (Ob) and diabetes (D).
c Case 3 was also hepatitis C virus positive.
