Modern Pathology

FIGURE 1

FROM:

Kupffer Cell Aggregation and Perivenular Distribution in Steatohepatitis

Jay H Lefkowitch, Jennifer H Haythe and Nicole Regent

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FIGURE 1.

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CD68 immunostaining of Kupffer cells in a case of mild steatohepatitis. A, low magnification shows prominent aggregated Kupffer cells near the central veins (arrows; magnification, 50 times). B, a portion of A shows a portal tract (P) and aggregated prominent Kupffer cells near the central vein (arrow). Individual elongated Kupffer cells in the midzonal and periportal regions are less conspicuous (magnification, 125 times). C, aggregated Kupffer cells with enlarged, rounded cell bodies and intracytoplasmic granules are present near mildly ballooned hepatocytes and the central vein (V; magnification, 325 times).

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