Modern Pathology

TABLE 5

FROM:

Distinct Clinical Features and Outcomes of Gastric Cancers with Microsatellite Instability

Hye Seung Lee, Seung Im Choi, Hyeon Kook Lee, Hee Sung Kim, Han-Kwang Yang, Gyeong Hoon Kang, Yong Il Kim, Byung Lan Lee and Woo Ho Kim

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TABLE 5. Univariate Analysis of Factors Related to Survival (Kaplan-Meier Product–Limit Method)

Factor% Patients Alive at 2 y% Patients Alive at 5 y P Valuea
Lauren's classification  0.006
 Intestinal87.082.6 
 Diffuse77.870.3 
 Mixed64.257.3 
pTNM stage  < 0.001
 I97.193.5 
 II86.277.6 
 III67.957.1 
 IV36.131.3 
MSI in AGC  0.046
 MSI-68.660.4 
 MSI+91.382.2 
MSI in 65 y or younger  0.039
 MSI-86.373.7 
 MSI+95.295.2 
TGFbetaRII in AGC  0.025
 Frameshift mutation (-)67.959.6 
 Frameshift mutation (+)95.285.2 
BAX in AGC  0.332
 Frameshift mutation (-)69.461.4 
 Frameshift mutation (+)86.773.3 

 AGC, advanced gastric carcinoma.

a The log-rank test was used to compare the survival curves.

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