TABLE 3

FROM:

Distinct Clinical Features and Outcomes of Gastric Cancers with Microsatellite Instability

Hye Seung Lee, Seung Im Choi, Hyeon Kook Lee, Hee Sung Kim, Han-Kwang Yang, Gyeong Hoon Kang, Yong Il Kim, Byung Lan Lee and Woo Ho Kim

TABLE 3. Molecular Analysis of 31 Gastric Cancers Positive for Microsatellite Instability (MSI+)

Case No.	BAT-25	Frameshift Mutation Analysis			MSH6	MSH3	E2F4	Immunostaining
		TGFRII	IGFIIR	BAX				MLH1	MSH2
A12	-1/wt	–	–	–	-1/wt	-3/wt	–	+
A13	MSI+	–	–	-1/wt	–	–	-9/wt	–	+
A32	MSI-	-2/wt	+1/wt	–	–	–	+6/wt	–	+
B01	MSI+	-1/wt	–	-1/wt	–	-1/wt	-3/wt	–	+
B05	MSI+	-1,-2/wt	–	-1/wt	–	–	-3/wt	–	+
B21	MSI+	-1,-2/wt	–	-1/wt	–	–	–	–	+
B24	MSI+	-1,-2/wt	–	-1/wt	-1/wt	-1/wt	-3/wt	–	–
B27	MSI+	-1/wt	–	-1/wt	–	-1/wt	–	–	+
B41	MSI+	-1/wt	–	-1/wt	–	-1/wt	-3/wt	–	+
B47	MSI+	-1,-2/wt	-1/wt	-1/wt	–	-1,-2/wt	-3/wt	+	–
B54	MSI-	-1/wt	–	–	–	–	–	+	+
C18	MSI+	-1/wt	–	-1/wt	–	–	–	+	+
C26	MSI+	-1/wt	–	–	–	–	+3/wt	–	+
C34	MSI+	-1/wt	–	-1/wt	-1/wt	–	-3,-6/wt	–	ND
C40	MSI+	-1,+1/wt	–	-1/wt	–	–	–	–	–
C48	MSI+	–	–	–	–	–	–	–	+
D17	MSI+	-1/wt	–	–	-1/wt	–	-3/wt	–	+
D22	MSI+	-1,-2/wt	–	-1/wt	–	-1/wt	-3/wt	–	+
D36	MSI+	-1,-2/wt	–	-1/wt	–	–	–	–	+
D45	MSI+	-1,+1/wt	–	–	-1/wt	–	-3/wt	+	+
E04	MSI+	–	–	–	–	–	–	–	+
E19	MSI+	-1/wt	+1	-1/wt	+1/wt	-1/wt	–	–	+
E30	MSI+	-1/wt	–	-1/wt	–	-1/wt	-3/wt	–	+
E49	MSI+	-1/wt	–	–	–	–	-3/wt	–	+
E53	MSI-	-1/wt	–	–	–	–	–	+	+
F06	MSI+	-1/wt	–	-1/wt	–	-1/wt	-6/wt	–	+
F13	MSI+	-1/wt	–	-1/wt	–	–	-3/wt	–	+
F36	MSI+	-1/wt	–	–	–	-1/wt	+3/wt	–	+
F39	MSI+	+1/wt	–	–	–	–	–	+	–
G45	MSI+	-1/wt	–	-1/wt	-1/wt	-1/wt	-9/wt	–	+
H58	MSI+	-1/wt	–	-1/wt	-1/wt	–	–	+	+
Total	27/31	28/31	3/31	19/31	7/31	12/31	19/31	24/31	4/31

 ND, not done; MSI+, microsatellite instability was found at BAT-25; MSI-, microsatellite instability was not found at BAT-25.