Modern Pathology - FIGURE 2 for article: Distinct Clinical Features and Outcomes of Gastric Cancers with Microsatellite Instability

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Distinct Clinical Features and Outcomes of Gastric Cancers with Microsatellite Instability

Hye Seung Lee, Seung Im Choi, Hyeon Kook Lee, Hee Sung Kim, Han-Kwang Yang, Gyeong Hoon Kang, Yong Il Kim, Byung Lan Lee and Woo Ho Kim

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FIGURE 2.

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Microscopic features of immunohistochemistry. MSI+ gastric cancer showed complete loss of hMLH1 protein, but adjacent lymphoid cells and stromal cells are positive for the protein (A, 200 $times$ ). In another MSI+ gastric cancer diminished hMSH2 protein expression were found (B, 200 $times$ ), but adjacent normal mucosa expressed hMSH2 protein. Immunostaining of p53 (C, 200 $times$ ), CEA (D, 100 $times$ ), and MUC1 (E, 200 $times$ ) and MUC2 (F, 200 $times$ ) proteins revealed positive expression pattern.

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