Modern Pathology

FIGURE 3

FROM:

Monoclonal Antibody D2-40, a New Marker of Lymphatic Endothelium, Reacts with Kaposi's Sarcoma and a Subset of Angiosarcomas

Harriette J Kahn, Denis Bailey and Alexander Marks

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FIGURE 3.

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Staining of lymphangioma and angiosarcoma with D2-40 or anti-CD31. AandD, consecutive paraffin sections of a lymphangioma were stained with D2-40 (A), showing strong positive staining of sinusoidal spaces, or with anti-CD31 (D), showing absence of staining. BandE, consecutive paraffin sections of an angiosarcoma were stained with D2-40 (B), showing absence of staining, or with anti-CD31 (E), showing diffuse positive staining. Cand F, consecutive paraffin sections of an angiosarcoma were stained with D2-40 (C), showing diffuse positive staining, or with anti-CD31 (F), likewise showing diffuse positive staining. Note absence of staining of the endothelial lining of a normal artery with D2-40 in C (arrow) and positive staining with anti-CD31 in F (arrowhead; original magnification, A to F: 100 times).

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