TABLE 4
FROM:
Autoimmune Gastritis: Distinct Histological and Immunohistochemical Findings Before Complete Loss of Oxyntic Glands
Michael Torbenson, Susan C Abraham, John Boitnott, John H Yardley and Tsung-Teh Wu
BACK TO ARTICLETABLE 4. Differentiating Autoimmune Gastritis (AG) from H. pylori Gastritis
| Feature | AG | H. Pylori Gastritis |
|---|---|---|
| Nature of inflammatory infiltrate | Diffuse or patchy lymphoplasmacytic infiltration of lamina propria, often with deep predominance | Often a bandlike infiltrate that is oriented more superficially and frequently shows activity |
| Gland destruction | Frequent | Infrequent |
| Parietal cell hyperplasia/hypertrophy | Frequent | Infrequent (unless on proton pump inhibitors) |
| ECL cell hyperplasia (at least linear) | Frequent | Infrequent |
| Predominantly affected part of stomach | Body | Antrum and body |
| Predominant location of metaplasia | Body (intestinal/pyloric) | Antrum (intestinal) |
