FIGURES AND TABLES
FROM:
Extranodal Follicular Dendritic Cell Sarcoma of the Head and Neck Region: Three New Cases, with a Review of the Literature
David A Biddle, Jae Y Ro, Gil S Yoon, Yap-Whang H Yong, Alberto G Ayala and Nelson G Ordonez
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FIGURE 1.
Case 1. Extranodal follicular dendritic cell sarcoma located beneath the stratified epithelium of the tonsil. The tumor is well circumscribed with pushing borders. Note the characteristic sprinkling of small lymphocytes throughout the tumor (hematoxylin and eosin stain, original magnification, 40 
).
FIGURE 2.
Case 2. Focally, the tumor forms vague circular whorls in a storiform growth pattern. Small lymphocytes and plasma cells are intermingled with syncytial-appearing neoplastic cells with smooth nuclear membranes (hematoxylin and eosin stain, original magnification, 100 ).
FIGURE 3.
Case 2. The tumor cell borders are indistinct, and the nuclei contain coarsely speckled chromatin with distinct nucleoli. Note the scattered multinucleate giant cells (
) (hematoxylin and eosin stain, original magnification, 200 ).
FIGURE 4.
Case 1. Focally multinucleated cells and mitotic figures () are found within the tumor (hematoxylin and eosin stain; original magnification, 600 ).
FIGURE 5.
Case 1. There is a background of small mature lymphocytes scattered throughout the tumor, as well as cuffing around a vessel (hematoxylin and eosin stain; original magnification, 100 ).
FIGURE 6.
Case 3. Tumor cells show nuclear pleomorphism (hematoxylin and eosin stain; original magnification, 400 ).
FIGURE 7.
Immunostains for CD21 and CD35, both for Case 1. (A) Immunostain for CD21 stains the tumor cells on the left strongly and diffusely (paraffin immunohistochemical stain; original magnification, 40 ). (B) Immunostain for CD35 highlights complex branching networks of neoplastic follicular dendritic cells (paraffin immunohistochemical stain; original magnification, 400 ).
