Modern Pathology

FIGURE 3

FROM:

Expression of Apocrine Differentiation Markers in Neuroendocrine Breast Carcinomas of Aged Women

Anna Sapino, Luisella Righi, Paola Cassoni, Mauro Papotti, Patrizia Gugliotta and Gianni Bussolati

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FIGURE 3.

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Kaplan-Meier curves of 35 patients. (A) Patients' survival is influenced by the histological type of tumors. The patients with mucinous and solid papillary carcinomas (producing some degree of mucin; a) have a significantly longer survival than patients with tumors of the other histological types (P = .05; b). (B) In short-term follow-up, the survival is not significantly modified by the immunophenotype (pure NE versus NE-apocrine tumors, P = .1), but 5 years after surgery, there is a tendency to a better prognosis for patients with NE-apocrine tumors. (C) The histological grade influenced prognosis; in fact, patients with G1 tumors are all alive at 13 years, those with G2 tumors have an intermediate prognosis; and all patients with G3 tumors had died by the 6-year follow-up. Patients with ER- (D) and PR- (E) tumors have significantly poorer prognosis than patients with ER+ and PR+ tumors.

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