FIGURE 1
FROM:
Expression of Apocrine Differentiation Markers in Neuroendocrine Breast Carcinomas of Aged Women
Anna Sapino, Luisella Righi, Paola Cassoni, Mauro Papotti, Patrizia Gugliotta and Gianni Bussolati
BACK TO ARTICLEFIGURE 1.
Expression of ChA and GCDFP-15 in different histotypes of NE breast cancers (mucinous, solid papillary, and solid cohesive types). A cribriform sheet of cells is floating within the mucin lakes in a mucinous NE–apocrine carcinoma (A). The same tumor is positive for ChA (B) and GCDFP-15 (C) in >50% of cells. In a solid papillary carcinoma, a solid nest of cells (upper) is separated from a mucin-producing area by sclerotic stroma (D). ChA is expressed only in the mucinous component (E), whereas GCDFP-15 is expressed in both counterparts (F). Solid cohesive NE–apocrine carcinoma showing rosettelike structures and peripheral cell palisading are reminiscent of carcinoid tumors (G). Both ChA (H) and GCDFP-15 (I) are expressed.
