TABLE 4
FROM:
Clinical, Histopathological, and Immunogenetic Analysis of Ocular Adnexal Lymphoproliferative Disorders: Characterization of MALT Lymphoma and Reactive Lymphoid Hyperplasia
Tomohiko Mannami, Tadashi Yoshino, Koichi Oshima, Sumie Takase, Eisaku Kondo, Nobuya Ohara, Hideki Nakagawa, Hiroshi Ohtsuki, Mine Harada and Tadaatsu Akagi
BACK TO ARTICLETABLE 4. Reactive Lymphoid Hyperplasia
| Case No. | Sex | Age (y) | Site/Bilaterality |  / Light-Chain Immunophenotype | Molecular Analysis by Using PCR | Treatment | Follow-Up Time (mo) | Status at Last Follow-Up | Clinical Course |
|---|---|---|---|---|---|---|---|---|---|
| 53 | M | 35 | Orbit, bilateral | Mixed | Not clonal | Cx | 103 | Died of NHL | DL developed to lymph nodes and parotid glands but not to the orbit |
| 54 | M | 44 | Orbit | Mixed | — | Observation | 31 | Alive | Second biopsy showed RLH, 20 mo; Rx was conducted, 21 mo |
| 55 | M | 62 | LG | Mixed | Not clonal | Observation | 65 | Alive | |
| 56 | M | 51 | Orbit | Mixed | Not clonal | Observation | 25 | Alive | |
| 57 | F | 70 | LG, bilateral | Mixed | Not clonal | Observation | 66 | Alive | Tumor of paranasal sinus and cervical lymph node also showed RLH |
| 58 | F | 55 | LG, bilateral | N.D. | Not clonal | — | — | Lost to follow-up | |
| 59 | M | 50 | Orbit | Mixed | Not clonal | Observation | 44 | Alive | Second biopsy showed RLH, 42 mo |
| 60 | M | 52 | LG, bilateral | Mixed | Not clonal | — | — | Lost to follow-up | |
| 61 | F | 47 | LG, bilateral | Mixed | Not clonal | — | — | Lost to follow-up | Cervical lymphadenopathy also showed RLH |
| 62 | M | 43 | LG | Mixed | Not clonal | Observation | 23 | Alive | |
| 63 | M | 28 | Orbit | Mixed | — | — | — | Lost to follow-up | |
| 64 | M | 31 | LG | Mixed | Not clonal | Observation | 18 | Alive | |
| 65 | M | 78 | Conjunctiva | N.D. | — | — | — | Lost to follow-up | |
| 66 | F | 44 | LG, bilateral | Mixed | Not clonal | Cx | 43 | Alive | Swelling of parotid glands showed RLH |
| 67 | F | 69 | LG, bilateral | Mixed | Not clonal | Observation | 54 | Alive | |
| 68 | F | 67 | LG | Mixed | Not clonal | Observation | 39 | Alive | |
| 69 | M | 69 | LG | Mixed | Not clonal | Cx | 36 | Alive | |
| 70 | F | 62 | LG | Mixed | Not clonal | Observation | 30 | Alive | |
| 71 | M | 56 | Orbit | Mixed | Not clonal | Observation | 22 | Alive | |
| 72 | M | 57 | LG | Mixed | Not clonal | Observation | 12 | Alive | |
| 73 | F | 73 | LG | Mixed | Not clonal | Observation | 11 | Alive | |
| 74 | M | 63 | LG, bilateral | Mixed | Not clonal | Observation | 8 | Alive |
M, male; F, female; LG, lacrimal gland; N.D., not determined; Cx, chemotherapy; NHL, non-Hodgkin's lymphoma; DL, diffuse large B-cell lymphoma; Rx, radiotherapy; RLH, reactive lymphoid hyperplasia.
