Modern Pathology

FIGURE 2

FROM:

An Immunophenotypic and Molecular Study of Primary Large B-Cell Lymphoma of Bone

David Huebner-Chan, Bernie Fernandes, Guisheng Yang and Megan S Lim

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FIGURE 2.

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Primary non-Hodgkin's lymphoma of bone with centroblastic morphology with significant nuclear pleomorphism, finely clumped chromatin, and two to three distinct nucleoli. Numerous mitotic figures and karyorrhectic debris are present. (A; hematoxylin and eosin staining, 400 times) The tumor cells express nuclear BCL-6 (B; 600 times), BCL-2 (C; 400 times), and p53 (D; 200 times).

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