TABLE 5
FROM:
Liver Pathology: Cirrhosis, Hepatitis, and Primary Liver Tumors. Update and Diagnostic Problems
Linda Ferrell
BACK TO ARTICLETABLE 5. PBC Versus CH
| PBC | CH | |
|---|---|---|
| Granulomas, portal | ++ | - |
| Loss of interlobular ducts | +++ | - |
| Inflammation of ducts | +++ | + (HCV, AIH) |
| Increased sinusoidal mononuclears | +++ |  (++HCV) |
| Lymphoid aggregates | ++ | + (++HCV) |
| Plasma cells | ++ | + (++AIH) |
| Cholestasis (bile plugs) | rare* | rare, periportal* |
| Mallory bodies | rare, periportal* | - |
PBC, primary biliary cirrhosis; CH, chronic hepatitis; HCV, hepatitis C; AIH, autoimmune hepatitis; +, present to a 1+ degree; ++, present to a 2+ degree; +++, present to a 3+ degree; -, not present; , minimal degree of involvement; *, not present until late stage.
From Ferrell LD. Liver and gallbladder pathology. In: Weidner N, editor. The difficult diagnosis in surgical pathology. Philadelphia: W.B. Saunders; 1996. p. 287. Reprinted with permission.
