Modern Pathology

FIGURES AND TABLES

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Value of the Mesothelium-Associated Antibodies Thrombomodulin, Cytokeratin 5/6, Calretinin, and CD44H in Distinguishing Epithelioid Pleural Mesothelioma from Adenocarcinoma Metastatic to the Pleura

P M Cury, D N Butcher, C Fisher, B Corrin and A G Nicholson

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FIGURE 1 - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact help@nature.com or the author

FIGURE 1.

Positive membrane staining of mesothelioma for thrombomodulin. Note the positive staining of endothelium (top left).

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FIGURE 2.

Positive cytoplasmic staining of mesothelioma for cytokeratin 5/6.

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FIGURE 3.

Positive membrane staining of mesothelioma for CD44H.

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FIGURE 4.

A case of epithelioid mesothelioma showing both nuclear and cytoplasmic staining for calretinin.

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FIGURE 5.

A case of colonic adenocarcinoma metastatic to the pleura showing cytoplasmic staining only for calretinin.

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FIGURE 6.

A, calretinin stains hyperplastic mesothelium, whereas adenocarcinoma cells are negative. B, calretinin stains submesothelial stromal cells within the pleura, whereas tumor cells remain negative.

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TABLE 1 - Expression of Mesothelioma-Associated Antibodies in Epithelioid Pleural Mesotheliomas and Metastatic Adenocarcinomas to the Pleura - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact help@nature.com or the author

TABLE 1 - Expression of Mesothelioma-Associated Antibodies in Epithelioid Pleural Mesotheliomas and Metastatic Adenocarcinomas to the Pleura.

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TABLE 2 - Differential Expression of Mesothelioma-Associated Antibodies in Adenocarcinomas Subgrouped According to Primary Site - Unfortunately we are unable to provide accessible alternative text for this. If you require assistance to access this image, please contact help@nature.com or the author

TABLE 2 - Differential Expression of Mesothelioma-Associated Antibodies in Adenocarcinomas Subgrouped According to Primary Site.

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