Modern Pathology

FIGURE 2

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TIA-1 Positive Tumor-Infiltrating Lymphocytes in Nevi and Melanomas

Stephen Lyle, Kevin E Salhany and David E Elder

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FIGURE 2.

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Radial growth phase melanoma with tumor-infiltrating lymphocytes stained for LCA (A) and TIA-1 (B). LCA+ tumor-infiltrating lymphocytes with brown membrane staining (arrows) are distinguished from melanophages with coarse, granular pigment (arrowheads). TIA-1+ tumor-infiltrating lymphocytes (arrows) can be distinguished from melanophages (arrowheads) by morphology (original magnification, 400 times).

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