Mucosal Immunology

FIGURE 2

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High frequencies of polyfunctional HIV-specific T cells are associated with preservation of mucosal CD4 T cells in bronchoalveolar lavage

J M Brenchley, K S Knox, A I Asher, D A Price, L M Kohli, E Gostick, B J Hill, C A Hage, Z Brahmi, A Khoruts, H L Twigg III, T W Schacker and D C Douek

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Figure 2.

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HIV infection frequency of CD4 T cells and alveolar macrophages in blood, GI tract, and BAL. (a) Percentage of HIV-infected blood central memory CD4 T cells and gut memory CD4 T cells determined by qPCR for HIV gag DNA. (b) Percentage of HIV-infected blood central memory CD4 T cells, BAL memory CD4 T cells, and BAL macrophages. (c) The ratio of CCR5 mRNA in BAL memory CD4 T cells compared to BAL macrophages in three individuals. Points depicting values for the same individual are linked by a line. BAL, bronchoalveolar lavage; GI, gastrointestinal.

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