Life Science Update November

November 2008

Biotechnology & Pharmacology
SciBX™ now available in HTML format and site license model
APS (Acta Pharmacologica Sinica), new to NPG in 2009

Genetics
   A look at next-generation sequencing technologies, presented by
   Nature Reviews Genetics and Nature Genetics
   NPG to publish the Journal of Human Genetics in 2009

Immunology
Focus on Glycobiology of the Immune System brought to you by
Immunology & Cell Biology

Microbiology
Evaluating Diagnostics: the CD4 guide brought to you by Nature Reviews Microbiology

Molecular & Cell Biology
   Nature Insight on Neuropsychiatric Diseases
   Focus on Reproductive Biology from Nature Medicine
   Focus on Cell Polarity from Nature Reviews Molecular Cell Biology
   FREE online access to featured Cell Research articles

Obesity
Metabolic Syndrome — now affecting over 25% of the world's population

NPG in the Community
   NPG continues to support the advancement of science in the community
   Learn more about the Imagine Science Film Festival, the Nature Awards for Mentoring in
   Science, Nature Debates and the Elucian Islands, NPG's virtual home in Second Life

Librarian Tools
   New Nature archive poster for librarians

Question of the Month
   Has your institution taken advantage of NPG's 15% discount off selected NPG journals?

***SciBX*™ now available in HTML format and site license model**

Starting with this week's issue published on November 6, SciBX: Science Business eXchange will be available in HTML format through NPG's regular site license model. The site license model and HTML format has been introduced in response to demand from institutional customers and users, and complements the existing 'per seat' model and PDF format. Both formats offer the same content. Ask your local sales representative for pricing.

Introductory offers are available on orders placed before November 30, 2008:

save 11% off list price
access all content back to volume 1, including post-cancellation rights

Bridging the gap between academic research and its commercial potential, SciBX identifies and evaluates new developments in science and technology that have investment potential within the biotechnology and pharmaceutical arena. Read more at www.nature.com/scibx.

APS (Acta Pharmacologica Sinica), new to NPG in 2009

In January 2009 NPG will add APS (Acta Pharmacologica Sinica) to its growing portfolio. APS is the official journal of the Chinese Pharmacological Society, and is sponsored by the Shanghai Institute of Materia Medica at the Chinese Academy of Sciences.

Topics of particular interest include:

Neuropharmacology
Cardiovascular and pulmonary pharmacology
Gastrointestinal and hepatic pharmacology
Genitourinary, renal and endocrine pharmacology
Immunopharmacology and inflammation
Drug discovery

Click here to learn more about APS. Register for a FREE trial today!

A look at next-generation sequencing technologies, presented by
Nature Reviews Genetics and Nature Genetics

DNA sequencing is undergoing a revolution. Sanger sequencing has reached its limits and is being replaced by a new generation of technologies that promise faster and cheaper delivery of sequencing information. Nature Genetics (*2007 Impact Factor 25.556) and Nature Reviews Genetics (*2007 Impact Factor 22.399) present a poster and podcast that explore the conceptual basis of these next-generation sequencing technologies, their myriad applications and challenges for the future.

Access the FREE poster and podcast today.

Produced with support from Applied Biosystems.

**NPG to publish the Journal of Human Genetics in 2009**

One of several journals new to NPG in 2009, the Journal of Human Genetics (JHG) seeks to promote research from all aspects of human genetics, including medical genetics and genomics. JHG is the official journal of the Japan Society for Human Genetics. Topics of particular interest include:

Medical genetics
Human genome analysis
Gene cloning and mapping
Human evolution
Cancer genetics
Gene therapy
Population genetics

Take advantage of everything JHG has to offer. Contact your local sales representative and request a FREE trial today.

Focus on Glycobiology of the Immune System brought to you by
Immunology & Cell Biology

Bringing you the latest on the glycobiology of the immune system, this FREE special feature and accompanying web focus from Immunology & Cell Biology explore the role glycans play in activating the adaptive and innate immune responses.

Encourage your users to view the web focus here.

Act now and save 15% off list price to Immunology & Cell Biology. This limited offer expires November 30, 2008.

More information about immunology products: click here.

Evaluating Diagnostics: the CD4 guide brought to you by
Nature Reviews Microbiology

Accurate CD4 counts are crucial laboratory markers for assessing immunodeficiency and the risk of disease progression in HIV-1 infection. HIV-1 causes a huge burden of morbidity and mortality, particularly in developing countries. This fourth supplement in the series on evaluating diagnostics brought to you by Nature Reviews Microbiology (*2007 Impact Factor 14.959) focuses on CD4 immunodiagnostics, which can be used to monitor CD4 counts, decide when to treat individuals with antivirals and whether treatments are effective.

Access the CD4 Guide online for FREE here.

Produced in collaboration with TDR.

Nature Insight on Neuropsychiatric Diseases

Neuropsychiatric diseases such as depression, schizophrenia and autism take a devastating toll on human society around the world. This FREE Nature Insight highlights recent progress made in our understanding of the molecular and cellular biology, genetics, and neural circuitry underlying neuropsychiatric diseases. Together, this research points to promising integrative approaches for tackling neuropsychiatric research in the post-genomic era, and strategies for developing future therapies.

Your users can read the Insight in the 16th October issue of Nature (*2007 Impact Factor 28.751) or access it online FREE of charge for the next six months.

Produced with an educational grant provided by Eli Lilly & Company.

Focus on Reproductive Biology from Nature Medicine

What findings are shaping our thinking on the field of reproductive biology? In which direction is this research discipline going? At a time when the scientific, social and financial relevance of this field is on the rise, we need dependable information to help us decide the direction our research must go. By bringing together input from top scientists, analysts and decision makers interested in the broad field of reproductive biology, this issue of Nature Medicine (*2007 Impact Factor 26.382) aims to become such a resource.

Your users can learn more about the science with the most impact for FREE here.

Supported by the Burroughs Welcome Fund and the March of Dimes.

Focus on Cell Polarity from Nature Reviews Molecular Cell Biology

Cell polarization is crucial for the development of unicellular and multicellular organisms, and is achieved through the coordinated actions of signalling pathways, membrane trafficking mechanisms and cytoskeletal dynamics. This special focus from
Nature Reviews Molecular Cell Biology (*2007 Impact Factor 31.921) aims to capture the status quo of cell polarity research in a range of different systems.

The focus content is FREE throughout the month of November. To access the focus articles, click here.

FREE online access to featured Cell Research articles

For a limited time NPG is offering FREE online access to a collection of some of the top articles published in
Cell Research in the past two years. Featured articles cover a range of topics including: apoptosis, stem cells, cell growth and differentiation, signal transduction, immunology, neuroscience and more.

Promote this offer in your institution and gauge your users' interest in Cell Research.

Click here and save 15% off list price to Cell Research. This limited offer expires November 30, 2008.

More information about molecular & cell biology products: click here.

Metabolic Syndrome — now affecting over 25% of the world's population

NPG brings you Metabolic Syndrome 2008 — a FREE web focus presenting a collection of original research articles from our academic titles that provide further insight into this global disease.

Metabolic Syndrome 2008 features content from:

American Journal of Hypertension
European Journal of Clinical Nutrition
International Journal of Impotence Research: The Journal of Sexual Medicine
International Journal of Obesity
Journal of Human Hypertension
Nature Clinical Practice Cardiovascular Medicine
Nature Clinical Practice Endocrinology & Metabolism
Obesity

View Metabolic Syndrome 2008 online FREE of charge.

Save 15% off list price to selected journals featured in Metabolic Syndrome 2008. This limited offer expires November 30, 2008.

NPG continues to support the advancement of science in the community

In October Nature was the proud sponsor of the Imagine Science Film Festival Awards in New York. Nature also presented its own Nature Awards for Mentoring in Science at a ceremony in Berlin. Congratulations to Klaas Bergmann, of the Technical University of Kaiserslautern, and Heinrich Betz, director of the Max Planck Institute for Brain Research in Frankfurt, who share the lifetime achievement award, and Peer Bork of the European Molecular Biology Laboratory in Heidelberg who received the mid-career award.

November 10th sees the second in a series of Nature Debates in London. Enhancing the Body is a panel debate focusing on the risks and benefits of research extending the human body: from speed, strength and healing to heat tolerance, pain thresholds and more. If London is too far to travel, fear not. Visit the Elucian Islands, NPG's newly expanded islands in virtual world Second Life, for events you can attend no matter where in the world you are. Upcoming events include a Virtual Conference on Climate Change and CO2 Storage on December 3rd, the debut virtual conference on the Elucian Islands.

New Nature archive poster for librarians

Site license access to the Nature archive provides your users with 139 years of Nature, the number one weekly science journal in the world. Download the new Nature archive poster FREE of charge and promote the complete Nature archive in your library. The poster is now available on the Librarian Gateway's Poster Page or via download here.

Has your institution taken advantage of NPG's 15% discount off selected NPG journals?

Find out the results of this poll in the December Life Science Update.

If you answered no to this question, click here for the complete list of journals that are eligible for this limited offer, available through November 30, 2008.

Last month's question: Do your users participate in online discussion forums on
Nature Network?

what was the response? 58.33% said yes, 41.67% said no.

pie chart

This e-update is designed to keep you aware of news about NPG's life science portfolio. Please forward this message to any of your colleagues who may find it of interest.

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Previous issues of NPG's Life Science Update are now available here.

*2007 Journal Citation Report (Thomson Reuters, 2008)

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SciBX™ now available in HTML format and site license model

A look at next-generation sequencing technologies, presented by Nature Reviews Genetics and Nature Genetics

NPG to publish the Journal of Human Genetics in 2009

Focus on Glycobiology of the Immune System brought to you by Immunology & Cell Biology

Evaluating Diagnostics: the CD4 guide brought to you byNature Reviews Microbiology