FIGURE 2
FROM:
Bortezomib is synergistic with rituximab and cyclophosphamide in inducing apoptosis of mantle cell lymphoma cells in vitro and in vivo
M Wang, X H Han, L Zhang, J Yang, J F Qian, Y K Shi, L W Kwak, J Romaguera and Q Yi
BACK TO ARTICLEFigure 2.
Dose-dependent apoptosis induced by BTZ. (a) Representative histograms showing Annexin-V positive apoptotic cells (Grant 519) in cultures with addition of different concentrations of BTZ, (b) BTZ-induced apoptosis in four MCL cell lines and (c) BTZ-induced apoptosis in primary tumor cells from three MCL patients. Cells were exposed to various concentrations of BTZ for 24 h and analyzed by Annexin-V-binding assay. Results of three independent experiments are shown.