TABLE OF CONTENTS
Volume 19, Issue 2 (February 2005)
Review |
Mini Reviews |
Commentary |
Original Manuscripts |
Biotechnical Methods Section (BTS) |
Spotlight Correspondence |
Correspondence |
Corrigendum
Keynote Address: Acute Leukemia Forum, San Francisco, 16 April 2004
Dose intensity and the toxicity and efficacy of allogeneic hematopoietic cell transplantation
F R Appelbaum
Leukemia 19: 171-175; doi:10.1038/sj.leu.2403609
Review
CD33-directed therapy with gemtuzumab ozogamicin in acute myeloid leukemia: progress in understanding cytotoxicity and potential mechanisms of drug resistance
M L Linenberger
Leukemia 19: 176-182; advance online publication, December 9, 2004; doi:10.1038/sj.leu.2403598
Mini Reviews
New insight into the molecular mechanisms of MLL-associated leukemia
Z-Y Li, D-P Liu and C-C Liang
Leukemia 19: 183-190; advance online publication, December 16, 2004; doi:10.1038/sj.leu.2403602
Genetic heterogeneity in multiple myeloma
F Magrangeas, L Lodé, S Wuilleme, S Minvielle and H Avet-Loiseau
Leukemia 19: 191-194; advance online publication, November 11, 2004; doi:10.1038/sj.leu.2403555
Commentary
High-mobility group A (HMGA) genes: from solid to liquid tumours?
J Boultwood and J S Wainscoat
Leukemia 19: 195-196; advance online publication, December 16, 2004; doi:10.1038/sj.leu.2403606
Original Manuscripts
Therapy Related MDS and AML
Amplification or duplication of chromosome band 21q22 with multiple copies of the AML1 gene and mutation of the TP53 gene in therapy-related MDS and AML
M K Andersen, D H Christiansen and J Pedersen-Bjergaard
Leukemia 19: 197-200; advance online publication, December 23, 2004; doi:10.1038/sj.leu.2403612
T-ALL
Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL
G K Przybylski, W A Dik, J Wanzeck, P Grabarczyk, S Majunke, J I Martin-Subero, R Siebert, G Dölken, W-D Ludwig, B Verhaaf, J J M van Dongen, C A Schmidt and A W Langerak
Leukemia 19: 201-208; doi:10.1038/sj.leu.2403619
T-Cell Lymphoma
Constitutive SOCS-3 expression protects T-cell lymphoma against growth inhibition by IFN
C Brender, P Lovato, V H Sommer, A Woetmann, A-M Mathiesen, C Geisler, M Wasik and N Ødum
Leukemia 19: 209-213; advance online publication, December 23, 2004; doi:10.1038/sj.leu.2403610
Infant ALL
Genetic polymorphism of NAD(P)H:quinone oxidoreductase is associated with an increased risk of infant acute lymphoblastic leukemia without MLL gene rearrangements
M Lanciotti, C Dufour, L Corral, P Di Michele, S Pigullo, G De Rossi, G Basso, A Leszl, M Luciani, L Lo Nigro, C Micalizzi, M G Valsecchi, A Biondi and R Haupt
Leukemia 19: 214-216; advance online publication, December 16, 2004; doi:10.1038/sj.leu.2403613
PNH
Large granular lymphocyte (LGL)-like clonal expansions in paroxysmal nocturnal hemoglobinuria (PNH) patients
A M Risitano, J P Maciejewski, P Muranski, M Wlodarski, C O'Keefe, E M Sloand and N S Young
Leukemia 19: 217-222; doi:10.1038/sj.leu.2403617
B-CLL
Role of B-cell antigen receptor-associated molecules and lipid rafts in CD5-induced apoptosis of B CLL cells
Y Renaudineau, S Nédellec, C Berthou, P M Lydyard, P Youinou and J-O Pers
Leukemia 19: 223-229; advance online publication, December 16, 2004; doi:10.1038/sj.leu.2403601
APL
Outcome of acute promyelocytic leukemia treated with all trans retinoic acid and chemotherapy in elderly patients: the European group experience
L Ades, S Chevret, S De Botton, X Thomas, H Dombret, B Beve, M Sanz, A Guerci, J S Miguel, J dela Serna, C Garo, A M Stoppa, O Reman, A Stamatoulas, M Fey, J Y Cahn, J J Sotto, J H Bourhis, A Parry, C Chomienne, L Degos and P Fenaux For the European APL Group
Leukemia 19: 230-233; advance online publication, November 25, 2004; doi:10.1038/sj.leu.2403597
Arsenic trioxide (ATO) and MEK1 inhibition synergize to induce apoptosis in acute promyelocytic leukemia cells
P Lunghi, A Tabilio, F Lo-Coco, P Pelicci and A Bonati
Leukemia 19: 234-244; advance online publication, November 11, 2004; doi:10.1038/sj.leu.2403585
Molecular Cytogenetics
Disruption and aberrant expression of HMGA2 as a consequence of diverse chromosomal translocations in myeloid malignancies
M D Odero, F H Grand, S Iqbal, F Ross, J P Roman, J L Vizmanos, J Andrieux, J L Laï, M J Calasanz and N C P Cross
Leukemia 19: 245-252; advance online publication, December 16, 2004; doi:10.1038/sj.leu.2403605
Effects of topoisomerase 2 inhibitors on the MLL gene in children receiving chemotherapy: a prospective study
A Ng, G M Taylor, R F Wynn and O B Eden
Leukemia 19: 253-259; advance online publication, December 9, 2004; doi:10.1038/sj.leu.2403599
Apoptose
Induction of apoptosis by proteasome inhibitors in B-CLL cells is associated with downregulation of CD23 and inactivation of Notch2
M Duechler, M Shehata, J D Schwarzmeier, A Hoelbl, M Hilgarth and R Hubmann
Leukemia 19: 260-267; advance online publication, November 25, 2004; doi:10.1038/sj.leu.2403592
WT1 Biology
Th1-biased humoral immune responses against Wilms tumor gene WT1 product in the patients with hematopoietic malignancies
F Wu, Y Oka, A Tsuboi, O A Elisseeva, K Ogata, H Nakajima, F Fujiki, T Masuda, M Murakami, S Yoshihara, K Ikegame, N Hosen, M Kawakami, M Nakagawa, T Kubota, T Soma, T Yamagami, M Tsukaguchi, H Ogawa, Y Oji, T Hamaoka, I Kawase and H Sugiyama
Leukemia 19: 268-274; advance online publication, November 11, 2004; doi:10.1038/sj.leu.2403539
Biotechnical Methods Section (BTS)
Ploidy, as detected by fluorescence in situ hybridization, defines different subgroups in multiple myeloma
S Wuilleme, N Robillard, L Lodé, F Magrangeas, H Beris, J-L Harousseau, J Proffitt, S Minvielle and H Avet-Loiseau for the Intergroupe Francophone du Myélome
Leukemia 19: 275-278; advance online publication, November 11, 2004; doi:10.1038/sj.leu.2403586
A novel approach to identify antigens recognized by CD4 T cells using complement-opsonized bacteria expressing a cDNA library
L van de Corput, P Chaux, E D van der Meijden, E De Plaen, J H Frederik Falkenburg and P van der Bruggen
Leukemia 19: 279-285; advance online publication, November 4, 2004; doi:10.1038/sj.leu.2403583
Spotlight Correspondence
Myeloid blast crisis evolving during imatinib treatment of an FIP1L1-PDGFR alpha-positive chronic myeloproliferative disease with prominent eosinophilia
N von Bubnoff, M Sandherr, G Schlimok, R Andreesen, C Peschel and J Duyster
Leukemia 19: 286-287; advance online publication, December 16, 2004; doi:10.1038/sj.leu.2403600
Biclonal blast crisis with a mutated ABL catalytic domain in a Ph, del (9q)-positive CML patient responsive to imatinib: drug resistance should be monitored in all patients irrespective of response status
G Alimena, M Breccia, M Mancini, D Diverio, M Nanni, M S De Propris, G Cimino, F Pane and F Mandelli
Leukemia 19: 287-289; advance online publication, November 11, 2004; doi:10.1038/sj.leu.2403584
Correspondence
All common p210 and p190 Bcr-abl variants can be targeted by RNA interference
L Wohlbold, H van der Kuip, A Moehring, G Granot, M Oren, H-P Vornlocher and W E Aulitzky
Leukemia 19: 290-292; advance online publication, November 25, 2004; doi:10.1038/sj.leu.2403603
Acadesine induces apoptosis in B cells from mantle cell lymphoma and splenic marginal zone lymphoma
C Campàs, A F Santidrián, A Domingo and J Gil
Leukemia 19: 292-294; advance online publication, November 18, 2004; doi:10.1038/sj.leu.2403593
e6-a2 BCR-ABL1 fusion in T-cell acute lymphoblastic leukemia
H Quentmeier, J Cools, R A F MacLeod, P Marynen, C C Uphoff and H G Drexler
Leukemia 19: 295-296; advance online publication, November 25, 2004; doi:10.1038/sj.leu.2403595
Telomeres and telomerase in paediatric patients with T-cell acute lymphoblastic leukaemia (T-ALL)
E Kleideiter, U Bangerter, M Schwab, P Boukamp, E Koscielniak, U Klotz and J Greil
Leukemia 19: 296-298; advance online publication, November 18, 2004; doi:10.1038/sj.leu.2403596
Acute lymphoblastic leukemia after tandem autologous stem cell transplantations for multiple myeloma
L G Lau, L K Tan, E S C Koay and T C Liu
Leukemia 19: 299-301; advance online publication, November 4, 2004; doi:10.1038/sj.leu.2403587
CTLA-4 overexpression in CD19+/CD5+ cells correlates with the level of cell cycle regulators and disease progression in B-CLL patients
A Kosmaczewska, L Ciszak, K Suwalska, D Wolowiec and I Frydecka
Leukemia 19: 301-304; advance online publication, November 18, 2004; doi:10.1038/sj.leu.2403588
Evaluation of real-time quantitative PCR machines for the monitoring of fusion gene transcripts using the Europe against cancer protocol
M Silvy, J Mancini, X Thirion, F Sigaux and J Gabert
Leukemia 19: 305-307; advance online publication, December 16, 2004; doi:10.1038/sj.leu.2403590
Hyperleukocytosis complicating lonafarnib treatment in patients with chronic myelomonocytic leukemia
A Buresh, J Perentesis, L Rimsza, S Kurtin, R Heaton, M Sugrue and A List
Leukemia 19: 308-310; advance online publication, November 11, 2004; doi:10.1038/sj.leu.2403569
Mutations in the BRAF and N-ras genes in childhood acute lymphoblastic leukaemia
B Gustafsson, S Angelini, B Sander, B Christensson, K Hemminki and R Kumar
Leukemia 19: 310-312; advance online publication, November 11, 2004; doi:10.1038/sj.leu.2403589
WHO-defined chronic neutrophilic leukemia: a long-term analysis of 12 cases and a critical review of the literature
M A Elliott, C A Hanson, G W Dewald, S A Smoley, T L Lasho and A Tefferi
Leukemia 19: 313-317; advance online publication, November 18, 2004; doi:10.1038/sj.leu.2403562
Predicting survival for myeloid leukemia after HLA-identical sibling donor allogeneic stem cell transplantation
G A Kennedy, J Butler, R Western, J Morton, G Hill and S Durrant
Leukemia 19: 317-318; advance online publication, November 25, 2004; doi:10.1038/sj.leu.2403549
Upregulation of asparagine synthetase and cell cycle arrest in t(12;21)-positive ALL
W A G Stams, M L den Boer, H B Beverloo, E R van Wering and R Pieters
Leukemia 19: 318-319; advance online publication, November 4, 2004; doi:10.1038/sj.leu.2403573
Reply to 'Upregulation of asparagine synthetase and cell cycle arrest in t(12;21) positive ALL' by Stams et al
O Krejci, J Starkova, B Otova, J Madzo, M Kalinova, O Hrusak and J Trka
Leukemia 19: 319-320; advance online publication, November 4, 2004; doi:10.1038/sj.leu.2403574
Reply to Krejci et al
W A G Stams, M L den Boer, H B Beverloo, E R van Wering and R Pieters
Leukemia 19: 320-321; advance online publication, November 4, 2004; doi:10.1038/sj.leu.2403576
Reply to Stams et al
O Krejci, J Starkova, B Otova, J Madzo, M Kalinova, O Hrusak and J Trka
Leukemia 19: 321; advance online publication, November 4, 2004; doi:10.1038/sj.leu.2403577
