TABLE OF CONTENTS

Volume 18, Issue 9 (September 2004)

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Leading Article

Circulating myeloid and lymphoid precursor dendritic cells are clonally involved in myelodysplastic syndromes FREE

L Ma, M Delforge, V Van Duppen, G Verhoef, B Emanuel, M Boogaerts, A Hagemeijer and P Vandenberghe

Leukemia 18: 1451-1456; advance online publication, July 29, 2004; doi:10.1038/sj.leu.2403430

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Commentary

Arsenic trioxide: expanding roles for an ancient drug? FREE

F Ravandi

Leukemia 18: 1457-1459; advance online publication, July 22, 2004; doi:10.1038/sj.leu.2403419

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Original Manuscripts

Treatment intensity significantly influencing fibrosis in bone marrow independently of the cytogenetic response: meta-analysis of the long-term results from two prospective controlled trials on chronic myeloid leukemia FREE

G Buesche, M Freund, R Hehlmann, A Georgii, A Ganser, H Hecker, H Heimpel, C Fonatsch, B Heinze, M Pfirrmann, S Holgado, A Schmeil, A Tobler, J Hasford, T Buhr, H-H Kreipe and the German CML Study Group

Leukemia 18: 1460-1467; advance online publication, July 29, 2004; doi:10.1038/sj.leu.2403451

BCR-ABL transcripts are early predictors for hematological relapse in chronic myeloid leukemia after hematopoietic cell transplantation with reduced intensity conditioning FREE

T Lange, M Deininger, R Brand, U Hegenbart, H Al-Ali, R Krahl, W Poenisch, L Uharek, S Leiblein, C Gentilini, E Petersdorf, R F Storb and D Niederwieser

Leukemia 18: 1468-1475; advance online publication, July 8, 2004; doi:10.1038/sj.leu.2403425

An update: 12-year follow-up of patients with hairy cell leukemia following treatment with 2-chlorodeoxyadenosine FREE

U Jehn, R Bartl, H Dietzfelbinger, T Haferlach and V Heinemann

Leukemia 18: 1476-1481; advance online publication, July 1, 2004; doi:10.1038/sj.leu.2403418

Transplantation studies in C3-deficient animals reveal a novel role of the third complement component (C3) in engraftment of bone marrow cells FREE

M Z Ratajczak, R Reca, M Wysoczynski, M Kucia, J T Baran, D J Allendorf, J Ratajczak and G D Ross

Leukemia 18: 1482-1490; advance online publication, July 29, 2004; doi:10.1038/sj.leu.2403446

In situ leukemic plasmacytoid dendritic cells pattern of chemokine receptors expression and in vitro migratory response FREE

N Bendriss-Vermare, L Chaperot, M Peoc'h, B Vanbervliet, M-C Jacob, F Briere, J-C Bensa, C Caux and J Plumas

Leukemia 18: 1491-1498; advance online publication, July 29, 2004; doi:10.1038/sj.leu.2403452

Mutational and expression analysis of the chromosome 12p candidate tumor suppressor genes in pre-B acute lymphoblastic leukemia FREE

A Montpetit, J Larose, G Boily, S Langlois, N Trudel and D Sinnett

Leukemia 18: 1499-1504; advance online publication, July 29, 2004; doi:10.1038/sj.leu.2403441

Hematological defects in the oc/oc mouse, a model of infantile malignant osteopetrosis FREE

C Blin-Wakkach, A Wakkach, P M Sexton, N Rochet and G F Carle

Leukemia 18: 1505-1511; advance online publication, July 29, 2004; doi:10.1038/sj.leu.2403449

Clinical characteristics and factors predicting evolution of asymptomatic IgM monoclonal gammopathies and IgM-related disorders FREE

E Morra, C Cesana, C Klersy, L Barbarano, M Varettoni, L Cavanna, B Canesi, E Tresoldi, S Miqueleiz, P Bernuzzi, A M Nosari and M Lazzarino on behalf of the HOST (Hematology/Oncology Studies and Trials) Group

Leukemia 18: 1512-1517; doi:10.1038/sj.leu.2403442

A clinical and pharmacological study of arsenic trioxide in advanced multiple myeloma patients FREE

P Rousselot, J Larghero, B Arnulf, J Poupon, B Royer, A Tibi, I Madelaine-Chambrin, P Cimerman, S Chevret, O Hermine, H Dombret, J Claude Brouet and J Paul Fermand

Leukemia 18: 1518-1521; advance online publication, July 22, 2004; doi:10.1038/sj.leu.2403424

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Bio-Technical Methods Section (BTS)

A diagnostic biochip for the comprehensive analysis of MLL translocations in acute leukemia FREE

N Maroc, A Morel, E Beillard, A L de La Chapelle, X Fund, M-J Mozziconacci, M Dupont, J-M Cayuela, J Gabert, A Koki, V Fert and F Hermitte

Leukemia 18: 1522-1530; doi:10.1038/sj.leu.2403439

Validation of BIOMED-2 multiplex PCR tubes for detection of TCRB gene rearrangements in T-cell malignancies FREE

J Droese, A W Langerak, P J T A Groenen, M Brüggemann, P Neumann, I L M Wolvers-Tettero, M C van Altena, M Kneba and J J M van Dongen

Leukemia 18: 1531-1538; advance online publication, July 29, 2004; doi:10.1038/sj.leu.2403428

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Spotlight Correspondence

Imatinib induces a cytogenetic response in blast crisis or interferon failure chronic myeloid leukemia patients with e19a2 BCR-ABL transcripts FREE

J-J Lee, H-J Kim, Y-J Kim, S Lee, J-Y Hwang, Y-L Kim and D-W Kim

Leukemia 18: 1539-1540; advance online publication, July 29, 2004; doi:10.1038/sj.leu.2403454

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Correspondence

Graft-versus-myeloma: are durable responses a clinical reality following donor lymphocyte infusion? FREE

K Peggs and S Mackinnon

Leukemia 18: 1541-1542; advance online publication, July 8, 2004; doi:10.1038/sj.leu.2403432

Response to "Graft-versus-myeloma: are durable responses a clinical reality following donor lymphocyte infusion?" by Peggs et al  FREE

F A Ayuk, A R Zander and N Kröger

Leukemia 18: 1542-1543; advance online publication, July 8, 2004; doi:10.1038/sj.leu.2403433

Susceptibility of malignant plasma cells to HA-1H specific lysis suggests a role for the minor histocompatibility antigen HA-1 in the graft-versus-myeloma effect FREE

P A Holloway, N Kaldenhoven, M van Dijk, A C Bloem, W de Lau, R van der Zee, B Kircher-Eibl, T Mutis and H M Lokhorst

Leukemia 18: 1543-1545; doi:10.1038/sj.leu.2403445

A novel partner gene CIP29 containing a SAP domain with MLL identified in infantile myelomonocytic leukemia FREE

Y Hashii, J Y Kim, A Sawada, S Tokimasa, F Hiroyuki, H Ohta, K Makiko, Y Takihara, K Ozono and J Hara

Leukemia 18: 1546-1548; advance online publication, July 29, 2004; doi:10.1038/sj.leu.2403450

Myeloid antigen positive acute lymphoblastic leukemia with the Philadelphia translocation and a jumping translocation of 1q in a child FREE

K D Montgomery, S S Winter, J D Frost, D Hardekopf, K Holt, M L Graham and K Foucar

Leukemia 18: 1548-1550; advance online publication, July 29, 2004; doi:10.1038/sj.leu.2403436

The use of housekeeping genes for real-time PCR-based quantification of fusion gene transcripts in acute myeloid leukemia FREE

M Weisser, T Haferlach, C Schoch, W Hiddemann and S Schnittger

Leukemia 18: 1551-1553; advance online publication, July 29, 2004; doi:10.1038/sj.leu.2403438

Screening for G-CSF receptor mutations in patients with secondary myeloid or lymphoid transformation of severe congenital neutropenia. A report from the French neutropenia register FREE

B Cassinat, C Bellanné-Chantelot, A Notz-Carrère, M L Menot, C Vaury, M Micheau, B Bader-Meunier, Y Perel, T Leblanc, J Donadieu, C Chomienne and le Groupe d'Etude des Neutropénies

Leukemia 18: 1553-1555; advance online publication, July 29, 2004; doi:10.1038/sj.leu.2403431

Osteoprotegerin serum levels in multiple myeloma and MGUS patients compared with age- and sex-matched healthy controls FREE

A Corso, A Dovio, C Rusconi, M L Sartori, C Klersy, M Varettoni, S Mangiacavalli, P Zappasodi, M Ventura, A Angeli and M Lazzarino

Leukemia 18: 1555-1557; advance online publication, July 8, 2004; doi:10.1038/sj.leu.2403429

Remission of adult acute lymphocytic leukaemia with Alemtuzumab FREE

J P Laporte, F Isnard, L Garderet, L Fouillard and N-C Gorin

Leukemia 18: 1557-1558; advance online publication, July 1, 2004; doi:10.1038/sj.leu.2403422

Expression of the MN1–TEL fusion protein in the human UCSD/AML1 leukemic cell line FREE

V Della Valle, L Guglielmi, M Busson, E C Zwarthoff, R Berger and O A Bernard

Leukemia 18: 1558-1560; advance online publication, July 1, 2004; doi:10.1038/sj.leu.2403420

Acute promyelocytic leukemia in a patient with multiple sclerosis following treatment with mitoxantrone FREE

A V Novoselac, S Reddy and J Sanmugarajah

Leukemia 18: 1561-1562; advance online publication, June 24, 2004; doi:10.1038/sj.leu.2403417

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Erratum

The paternal chromosome 9 and the maternal chromosome 22 are preferentially rearranged in chronic myeloid leukaemia FREE

R Olicio, M B Rivero and H N Seuánez

Leukemia 18: 1563; doi:10.1038/sj.leu.2403455

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Corrigendum

Analysis of IgH translocations, chromosome 13q14 and 17p13.1(p53) deletions by fluorescence in situ hybridization in Waldenstrom's macroglobulinemia: a single center study of 22 cases FREE

H Chang, S Samiee, D Li, B Patterson, C I Chen and A Keith Stewart

Leukemia 18: 1564; doi:10.1038/sj.leu.2403456

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