TABLE OF CONTENTS
Volume 18, Issue 6 (June 2004)
Review |
Molecular Targets for Therapy (MTT) |
Original Manuscripts |
Spotlight Correspondence |
Correspondence |
Corrigendum |
Erratum
Meeting Report
Ponte di Legno Working Group: statement on the right of children with leukemia to have full access to essential treatment and report on the Sixth International Childhood Acute Lymphoblastic Leukemia Workshop FREE
C-H Pui, M Schrappe, G Masera, J Nachman, H Gadner, O B Eden, W E Evans and P Gaynon
Leukemia 18: 1043-1053; advance online publication, April 15, 2004; doi:10.1038/sj.leu.2403365
Review
Crosstalk between angiogenesis and lymphangiogenesis in tumor progression FREE
C Scavelli, A Vacca, G Di Pietro, F Dammacco and D Ribatti
Leukemia 18: 1054-1058; advance online publication, April 1, 2004; doi:10.1038/sj.leu.2403355
Molecular Targets for Therapy (MTT)
Hox expression in AML identifies a distinct subset of patients with intermediate cytogenetics FREE
J Roche, C Zeng, A Barón, S Gadgil, R M Gemmill, I Tigaud, X Thomas and H A Drabkin
Leukemia 18: 1059-1063; advance online publication, April 15, 2004; doi:10.1038/sj.leu.2403366
Original Manuscripts
Acute Lymphoblastic Leukemia: MLL-AF4 and Cell Cycle
Modulation of cell cycle by graded expression of MLL-AF4 fusion oncoprotein FREE
C Caslini, A Serna, V Rossi, M Introna and A Biondi
Leukemia 18: 1064-1071; advance online publication, February 26, 2004; doi:10.1038/sj.leu.2403321
Acute Lymphoblastic Leukemia: Treatment
Asparaginase pharmacodynamics differ by formulation among children with newly diagnosed acute lymphoblastic leukemia FREE
L J Hak, M V Relling, C Cheng, D Pei, B Wang, J T Sandlund, J Rubnitz and C-H Pui
Leukemia 18: 1072-1077; advance online publication, April 1, 2004; doi:10.1038/sj.leu.2403351
Multiple Myeloma: Treatment
G3139, a Bcl-2 antisense oligodeoxynucleotide, induces clinical responses in VAD refractory myeloma FREE
N W C J van de Donk, O de Weerdt, G Veth, M Eurelings, E van Stralen, S R Frankel, A Hagenbeek, A C Bloem and H M Lokhorst
Leukemia 18: 1078-1084; advance online publication, April 15, 2004; doi:10.1038/sj.leu.2403363
The dose of infused lymphocytes in the autograft directly correlates with clinical outcome after autologous peripheral blood hematopoietic stem cell transplantation in multiple myeloma FREE
L F Porrata, M A Gertz, S M Geyer, M R Litzow, D A Gastineau, S B Moore, A A Pineda, K L Bundy, D J Padley, D Persky, M Q Lacy, A Dispenzieri, D S Snow and S N Markovic
Leukemia 18: 1085-1092; advance online publication, March 25, 2004; doi:10.1038/sj.leu.2403341
Chronic Lymphocytic Leukemia: Treatment
Consolidation with alemtuzumab in patients with chronic lymphocytic leukemia (CLL) in first remission – experience on safety and efficacy within a randomized multicenter phase III trial of the German CLL Study Group (GCLLSG) FREE
C-M Wendtner, M Ritgen, C D Schweighofer, G Fingerle-Rowson, H Campe, G Jäger, B Eichhorst, R Busch, H Diem, A Engert, S Stilgenbauer, H Döhner, M Kneba, B Emmerich, M Hallek and the German CLL Study Group (GCLLSG)
Leukemia 18: 1093-1101; advance online publication, April 8, 2004; doi:10.1038/sj.leu.2403354
Residual Disease in Non-Hodgkin's Lymphomas
Prognostic significance of molecular staging by PCR-amplification of immunoglobulin gene rearrangements in diffuse large B-cell lymphoma (DLBCL) FREE
G Mitterbauer-Hohendanner, C Mannhalter, K Winkler, M Mitterbauer, C Skrabs, A Chott, I Simonitsch-Klupp, A Glei
, K Lechner and U Jaeger
Leukemia 18: 1102-1107; advance online publication, April 15, 2004; doi:10.1038/sj.leu.2403376
Gene Translocations and Deletions in Myeloid Malignancies
Translocation t(2;3)(p15–23;q26–27) in myeloid malignancies: report of 21 new cases, clinical, cytogenetic and molecular genetic features FREE
M Stevens-Kroef, B Poppe, S van Zelderen-Bhola, E van den Berg, M van der Blij-Philipsen, A Geurts van Kessel, R Slater, G Hamers, L Michaux, F Speleman and A Hagemeijer
Leukemia 18: 1108-1114; advance online publication, April 15, 2004; doi:10.1038/sj.leu.2403346
RT-PCR and FISH analysis of acute myeloid leukemia with t(8;16)(p11;p13) and chimeric MOZ and CBP transcripts: breakpoint cluster region and clinical implications FREE
H H Schmidt, S Strehl, D Thaler, D Strunk, H Sill, W Linkesch, U Jäger, W Sperr, H T Greinix, M König, W Emberger and O A Haas
Leukemia 18: 1115-1121; advance online publication, April 15, 2004; doi:10.1038/sj.leu.2403353
Inositide-specific phospholipase c 
1 gene deletion in the progression of myelodysplastic syndrome to acute myeloid leukemia FREE
V R Lo Vasco, G Calabrese, L Manzoli, G Palka, A Spadano, E Morizio, P Guanciali-Franchi, D Fantasia and L Cocco
Leukemia 18: 1122-1126; advance online publication, April 15, 2004; doi:10.1038/sj.leu.2403368
Platelets in Chronic Myelogenous Leukemia
Constitutively activated phosphatidylinositol 3-kinase primes platelets from patients with chronic myelogenous leukemia for thrombopoietin-induced aggregation FREE
Y Kubota, T Tanaka, H Ohnishi, A Kitanaka, Y Okutani, T Taminato, T Ishida and H Kamano
Leukemia 18: 1127-1137; advance online publication, April 15, 2004; doi:10.1038/sj.leu.2403370
Spotlight Correspondence
Visual disturbance due to retinal edema as a complication of imatinib FREE
E Kusumi, A Arakawa, M Kami, D Kato, K Yuji, Y Kishi, N Murashige, S Miyakoshi, J Ueyama, S Morinaga, S Taniguchi and Y Muto
Leukemia 18: 1138-1139; advance online publication, April 15, 2004; doi:10.1038/sj.leu.2403364
Correspondence
Clonal chromosomal abnormalities in the Philadelphia chromosome negative cells of chronic myeloid leukemia patients treated with imatinib FREE
N Guilbert-Douet, F Morel, M-J Le Bris, C Berthou, P Morice, P Bourquard and M D Braekeleer
Leukemia 18: 1140-1142; advance online publication, April 15, 2004; doi:10.1038/sj.leu.2403361
Somatic PTPN11 mutation with a heterogeneous clonal origin in children with juvenile myelomonocytic leukemia FREE
H Shimada, T Mori, N Shimasaki, K Shimizu, T Takahashi and K Kosaki
Leukemia 18: 1142-1144; advance online publication, April 15, 2004; doi:10.1038/sj.leu.2403374
Nucleolar localization of the carboxy-truncated form of the signal transducer and activator of transcription 5 (STAT5
) detected in CML and AML5 FREE
N Touche, H Schohn, C Bonnet, J Buisine, F Plénat, C Philippe and P Jonveaux
Leukemia 18: 1144-1145; advance online publication, April 15, 2004; doi:10.1038/sj.leu.2403371
Transcriptional repression of the p15 gene predicts the clinical outcome of acute myeloblastic leukemia with intermediate and adverse cytogenetics FREE
N Matsuno, K Hoshino, T Nanri, T Kawakita, H Mitsuya and N Asou
Leukemia 18: 1146-1148; advance online publication, April 15, 2004; doi:10.1038/sj.leu.2403362
Loss of heterozygosity of the polymorphic PIG3 microsatellite with low frequency in de novo acute myeloid leukemias FREE
J F Nomdedéu, G Perea, C Estivill, A Lasa, S Brunet, A Aventín and J Sierra
Leukemia 18: 1148-1149; advance online publication, April 15, 2004; doi:10.1038/sj.leu.2403379
TNF-
receptor 1 expression on acute myeloid leukemic blasts predicts differentiation into leukemic dendritic cells FREE
I Houtenbos, T M Westers, T D de Gruijl, R J Scheper, G J Ossenkoppele and A A van de Loosdrecht
Leukemia 18: 1149-1153; advance online publication, April 15, 2004; doi:10.1038/sj.leu.2403359
Amplification of the ABL gene in T-cell acute lymphoblastic leukemia FREE
K E Barber, M Martineau, L Harewood, M Stewart, E Cameron, J C Strefford, S Rutherford, T D Allen, Z J Broadfield, K L Cheung, R L Harris, G R Jalali, A V Moorman, H M Robinson and C J Harrison
Leukemia 18: 1153-1156; advance online publication, April 1, 2004; doi:10.1038/sj.leu.2403357
Graft-versus-leukemia effect in acute lymphoblastic leukemia: the importance of tumor burden and early detection FREE
S M Bradfield, J P Radich and M R Loken
Leukemia 18: 1156-1158; advance online publication, March 25, 2004; doi:10.1038/sj.leu.2403352
All-trans retinoic acid reduced skin involvement of adult T-cell leukemia FREE
Y Maeda, T Yamaguchi, S Ueda, H Miyazato, M Matsuda and A Kanamaru
Leukemia 18: 1159-1160; advance online publication, April 15, 2004; doi:10.1038/sj.leu.2403356
Analysis of IgH translocations, chromosome 13q14 and 17p13.1(p53) deletions by fluorescence in situ hybridization in Waldenstrom's macroglobulinemia: a single center study of 22 cases FREE
H Chang, S Samiee, D Li, B Patterson, C I Chen and A Keith Stewart
Leukemia 18: 1160-1162; advance online publication, April 22, 2004; doi:10.1038/sj.leu.2403369
Increased sex concordance of sibling pairs with chronic lymphocytic leukemia FREE
G S Sellick, R Allinson, E Matutes, D Catovsky and R S Houlston
Leukemia 18: 1162-1163; advance online publication, April 15, 2004; doi:10.1038/sj.leu.2403360
Corrigendum
Activation of the HIF pathway in childhood ALL, prognostic implications of VEGF FREE
S Wellmann, M Guschmann, W Griethe, C Eckert, Av Stackelberg, C Lottaz, E Moderegger, H G Einsiedel, K-U Eckardt, G Henze and K Seeger
Leukemia 18: 1164; doi:10.1038/sj.leu.2403394
Erratum
Predicting survival for myeloid leukemia after HLA-identical sibling donor allogeneic stem cell transplantation FREE
D Gallardo, R De la Cámara, A Torres, S Brunet, A Jiménez, J C Vallejo, G Sanz, D Serrano, E Carreras, C Martín, C Sanz-Rodríguez, J Sierra, I Espigado, D Caballero and J J Berlanga
Leukemia 18: 1165-1167; doi:10.1038/sj.leu.2403397
