TABLE OF CONTENTS
Volume 18, Issue 11 (November 2004)
Reviews |
Commentaries |
Leading Article |
Molecular Targets for Therapy (MTT) |
Original Manuscripts |
Bio-Technical Methods Section |
Correspondence
Editorial
Order and disorder in the vascular network FREE
D Guidolin, B Nico, G Mazzocchi, A Vacca, G G Nussdorfer and D Ribatti
Leukemia 18: 1745-1750; doi:10.1038/sj.leu.2403526
Reviews
Inhibitor of apoptosis proteins: new therapeutic targets in hematological cancer? FREE
A O de Graaf, T de Witte and J H Jansen
Leukemia 18: 1751-1759; advance online publication, September 30, 2004; doi:10.1038/sj.leu.2403493
Regulation of hematopoietic stem cell growth FREE
E C Attar and D T Scadden
Leukemia 18: 1760-1768; advance online publication, September 30, 2004; doi:10.1038/sj.leu.2403515
Commentaries
Another step forward towards improved outcome after HLA-haploidentical stem cell transplantation FREE
C Peters
Leukemia 18: 1769-1771; advance online publication, September 30, 2004; doi:10.1038/sj.leu.2403527
Clinical trials in AML of the elderly: should we change our methodology? FREE
E Estey
Leukemia 18: 1772-1774; advance online publication, September 23, 2004; doi:10.1038/sj.leu.2403530
Leading Article
AID is expressed in germinal center B-cell-like and activated B-cell-like diffuse large-cell lymphomas and is not correlated with intraclonal heterogeneity FREE
I S Lossos, R Levy and A A Alizadeh
Leukemia 18: 1775-1779; advance online publication, September 16, 2004; doi:10.1038/sj.leu.2403488
Molecular Targets for Therapy (MTT)
Potent antileukemic interactions between flavopiridol and TRAIL/Apo2L involve flavopiridol-mediated XIAP downregulation FREE
R R Rosato, Y Dai, J A Almenara, S C Maggio and S Grant
Leukemia 18: 1780-1788; advance online publication, September 16, 2004; doi:10.1038/sj.leu.2403491
Original Manuscripts
Therapy
Treatment of relapsed acute myeloid leukemia after allogeneic bone marrow transplantation with chemotherapy followed by G-CSF-primed donor leukocyte infusion: a high incidence of isolated extramedullary relapse FREE
S-J Choi, J-H Lee, J-H Lee, S Kim, M Seol, Y-S Lee, J-S Lee, W-K Kim, H-S Chi and K-H Lee
Leukemia 18: 1789-1797; advance online publication, September 23, 2004; doi:10.1038/sj.leu.2403523
APL
Phase III study of all-trans retinoic acid in previously untreated patients 61 years or older with acute myeloid leukemia FREE
R F Schlenk, S Fröhling, F Hartmann, J Th Fischer, A Glasmacher, F del Valle, W Grimminger, K Götze, C Waterhouse, R Schoch, H Pralle, H G Mergenthaler, M Hensel, E Koller, H Kirchen, J Preiss, H Salwender, H G Biedermann, S Kremers, F Griesinger, A Benner, B Addamo, K Döhner, R Haas and H Döhner for the AML Study Group Ulm
Leukemia 18: 1798-1803; advance online publication, September 23, 2004; doi:10.1038/sj.leu.2403528
Analysis of p73 expression pattern in acute myeloid leukemias: lack of 
N-p73 expression is a frequent feature of acute promyelocytic leukemia FREE
M G Rizzo, E Giombini, D Diverio, M Vignetti, A Sacchi, U Testa, F Lo-Coco and G Blandino
Leukemia 18: 1804-1809; advance online publication, September 16, 2004; doi:10.1038/sj.leu.2403483
CLL
Apoptotic tumor cells are superior to tumor cell lysate, and tumor cell RNA in induction of autologous T cell response in B-CLL FREE
P Kokhaei, A Choudhury, R Mahdian, J Lundin, A Moshfegh, A Österborg and H Mellstedt
Leukemia 18: 1810-1815; advance online publication, September 23, 2004; doi:10.1038/sj.leu.2403517
Methylenetetrahydrofolate reductase (MTHFR) gene 677C>T and 1298A>C polymorphisms are associated with differential apoptosis of leukemic B cells in vitro and disease progression in chronic lymphocytic leukemia FREE
H Nückel, U H Frey, J Dürig, U Dührsen and W Siffert
Leukemia 18: 1816-1823; advance online publication, September 16, 2004; doi:10.1038/sj.leu.2403484
ALL
Retrospective comparison of qualitative and quantitative reverse transcriptase polymerase chain reaction in diagnosing and monitoring the ALL1-AF4 fusion transcript in patients with acute lymphoblastic leukaemia FREE
L Elia, E Gottardi, G Floriddia, R Grillo, F Ciambelli, M Luciani, P Chiusolo, R Invernizzi, G Meloni, R Foà, G Saglio and G Cimino
Leukemia 18: 1824-1830; advance online publication, August 19, 2004; doi:10.1038/sj.leu.2403448
Childhood AML
PTPN11 mutations in pediatric patients with acute myeloid leukemia: results from the Children's Cancer Group FREE
M L Loh, M G Reynolds, S Vattikuti, R B Gerbing, T A Alonzo, E Carlson, J W Cheng, C M Lee, B J Lange and S Meshinchi
Leukemia 18: 1831-1834; advance online publication, September 16, 2004; doi:10.1038/sj.leu.2403492
Bone Marrow Transplantation
Purified donor NK-lymphocyte infusion to consolidate engraftment after haploidentical stem cell transplantation FREE
J R Passweg, A Tichelli, S Meyer-Monard, D Heim, M Stern, T Kühne, G Favre and A Gratwohl
Leukemia 18: 1835-1838; advance online publication, September 30, 2004; doi:10.1038/sj.leu.2403524
Signal Transduction
Restoration of SHIP activity in a human leukemia cell line downregulates constitutively activated phosphatidylinositol 3-kinase/Akt/GSK-3
signaling and leads to an increased transit time through the G1 phase of the cell cycle FREE
S Horn, E Endl, B Fehse, M M Weck, G W Mayr and M Jücker
Leukemia 18: 1839-1849; advance online publication, September 30, 2004; doi:10.1038/sj.leu.2403529
Identification of novel direct transcriptional targets of glucocorticoid receptor FREE
M U, L Shen, T Oshida, J Miyauchi, M Yamada and T Miyashita
Leukemia 18: 1850-1856; advance online publication, September 23, 2004; doi:10.1038/sj.leu.2403516
Differentiation
CPEC induces erythroid differentiation of human myeloid leukemia K562 cells through CTP depletion and p38 MAP kinase FREE
M Huang, Y Wang, M Collins and L M Graves
Leukemia 18: 1857-1863; advance online publication, September 16, 2004; doi:10.1038/sj.leu.2403490
Mouse Model
Impaired myelopoiesis in mice devoid of interferon regulatory factor 1 FREE
U Testa, E Stellacci, E Pelosi, P Sestili, M Venditti, R Orsatti, A Fragale, E Petrucci, L Pasquini, F Belardelli, L Gabriele and A Battistini
Leukemia 18: 1864-1871; advance online publication, September 16, 2004; doi:10.1038/sj.leu.2403472
Lymphoma
Suppressor of cytokine signaling 3 expression in anaplastic large cell lymphoma FREE
J H Cho-Vega, G Z Rassidakis, H M Amin, P Tsioli, K Spurgers, Y K Remache, F Vega, A H Goy, F Gilles and L Jeffrey Medeiros
Leukemia 18: 1872-1878; advance online publication, September 23, 2004; doi:10.1038/sj.leu.2403495
Myeloma
Both IGH translocations and chromosome 13q deletions are early events in monoclonal gammopathy of undetermined significance and do not evolve during transition to multiple myeloma FREE
H Kaufmann, J Ackermann, C Baldia, T Nösslinger, R Wieser, S Seidl, V Sagaster, H Gisslinger, U Jäger, M Pfeilstöcker, C Zielinski and J Drach
Leukemia 18: 1879-1882; advance online publication, September 23, 2004; doi:10.1038/sj.leu.2403518
PI3-K/AKT/FKHR and MAPK signaling cascades are redundantly stimulated by a variety of cytokines and contribute independently to proliferation and survival of multiple myeloma cells FREE
S Lentzsch, M Chatterjee, M Gries, K Bommert, H Gollasch, B Dörken and R C Bargou
Leukemia 18: 1883-1890; advance online publication, September 9, 2004; doi:10.1038/sj.leu.2403486
The SCID-rab model: a novel in vivo system for primary human myeloma demonstrating growth of CD138-expressing malignant cells FREE
K Yata and S Yaccoby
Leukemia 18: 1891-1897; advance online publication, September 23, 2004; doi:10.1038/sj.leu.2403513
Bio-Technical Methods Section
RNA-based gene transfer for adult stem cells and T cells FREE
E Smits, P Ponsaerts, M Lenjou, G Nijs, D R Van Bockstaele, Z N Berneman and V F I Van Tendeloo
Leukemia 18: 1898-1902; advance online publication, September 23, 2004; doi:10.1038/sj.leu.2403463
Correspondence
Plasma-cell leukemia and human herpesvirus 8 infection FREE
R Duprez, V Lacoste, S Hermouet, X Troussard, F Valensi, H Merle-Beral and A Gessain
Leukemia 18: 1903-1904; advance online publication, September 23, 2004; doi:10.1038/sj.leu.2403509
Unrelated cord blood transplantation for adult patients with acute lymphoblastic leukemia FREE
J Ooi, T Iseki, S Takahashi, A Tomonari, A Tojo and S Asano
Leukemia 18: 1905-1907; advance online publication, September 23, 2004; doi:10.1038/sj.leu.2403514
Pretransplant imatinib can improve the outcome of nonmyeloablative stem cell transplantation without increasing the morbidity in Philadelphia chromosome-positive chronic myeloid leukemia FREE
D-W Kim, Y-J Chung, S Lee, Y-J Kim, N-G Chung, J A Kim, I-H Oh, T-G Kim, Y-L Kim, H-G Goh, S-H Kim, B Cho, H-J Kim, C-K Min, J W Lee, J Y Jin, C-W Han, J W Kim, W-S Min, H-K Kim, C-C Kim and H J Kim
Leukemia 18: 1907-1909; advance online publication, September 9, 2004; doi:10.1038/sj.leu.2403502
Centrosome abnormalities in ALK-positive anaplastic large-cell lymphoma FREE
R A Ventura, J I Martin-Subero, U Knippschild, R D Gascoyne, G Delsol, D Y Mason and R Siebert
Leukemia 18: 1910-1911; advance online publication, September 23, 2004; doi:10.1038/sj.leu.2403470
Hairy cell leukemia with large cells: long disease course with adequate response to therapy FREE
X Sun, H M Amin, E J Freireich, M J Keating, H M Kantarjian, C A Koller, S M O'Brien, F Giles and M Albitar
Leukemia 18: 1912-1914; advance online publication, September 16, 2004; doi:10.1038/sj.leu.2403506
Breast cancer resistance protein (BCRP/ABCG2) does not confer resistance to gemtuzumab ozogamicin and calicheamicin-
1 in acute myeloid leukemia cells FREE
R B Walter, B W Raden, J Thompson, D A Flowers, H-P Kiem, I D Bernstein and M L Linenberger
Leukemia 18: 1914-1917; advance online publication, September 16, 2004; doi:10.1038/sj.leu.2403461
Apparent absence of BRCA2 protein in a proportion of acute myeloid leukemia cell lines FREE
F Chen, A L Medhurst, J P de Winter, Q Waisfisz, M A Rooimans, A B Oostra, S Meyer, K J Zhang, B Xia, G Pals, F Arwert, C M Zwaan and H Joenje
Leukemia 18: 1918-1920; advance online publication, September 9, 2004; doi:10.1038/sj.leu.2403473
The GSTT1 deletion polymorphism is associated with initial response to glucocorticoids in childhood acute lymphoblastic leukemia FREE
B Meissner, M Stanulla, W-D Ludwig, J Harbott, A Möricke, K Welte and M Schrappe
Leukemia 18: 1920-1923; advance online publication, September 30, 2004; doi:10.1038/sj.leu.2403521
Fludarabine therapy in patients with splenic lymphoma with villous lymphocytes: an update FREE
F Lefrère, V Lévy, S François, R Delarue, N Ifrah, H Tilly, F Valensi, X Troussard, B Varet and O Hermine
Leukemia 18: 1924-1925; advance online publication, September 23, 2004; doi:10.1038/sj.leu.2403440
