TABLE OF CONTENTS

Volume 17, Issue 4 (April 2003)

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Spotlight

Perspectives on the treatment of chronic phase and advanced phase CML and Philadelphia chromosome positive ALL  FREE

C A Schiffer, R Hehlmann and R Larson

Leukemia 17: 691-699; doi:10.1038/sj.leu.2402879

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Original Manuscripts

Clinical heterogeneity in childhood acute lymphoblastic leukemia with 11q23 rearrangements FREE

C-H Pui, J M Chessells, B Camitta, A Baruchel, A Biondi, J M Boyett, A Carroll, O B Eden, W E Evans, H Gadner, J Harbott, D O Harms, C J Harrison, P L Harrison, N Heerema, G Janka-Schaub, W Kamps, G Masera, J Pullen, S C Raimondi, S Richards, H Riehm, S Sallan, H Sather, J Shuster, L B Silverman, M G Valsecchi, E Vilmer, Y Zhou, P S Gaynon and M Schrappe

Leukemia 17: 700-706; doi:10.1038/sj.leu.2402883

Immunophenotype CD34 in AML

HLA-DR antigen-negative acute myeloid leukemia FREE

M Wetzler, B K McElwain, C C Stewart, L Blumenson, A Mortazavi, L A Ford, J L Slack, M Barcos, S Ferrone and M R Baer

Leukemia 17: 707-715; doi:10.1038/sj.leu.2402865

Quantification and cytokine production of circulating lymphoid and myeloid cells in acute myelogenous leukaemia  FREE

N Panoskaltsis, C D L Reid and S C Knight

Leukemia 17: 716-730; doi:10.1038/sj.leu.2402835

Characteristics of t(8;21) acute myeloid leukemia (AML) with additional chromosomal abnormality: concomitant trisomy 4 may constitute a distinctive subtype of t(8;21) AML FREE

K Nishii, E Usui, N Katayama, F Lorenzo V, K Nakase, T Kobayashi, H Miwa, M Mizutani, I Tanaka, K Nasu, H Dohy, T Kyo, M Taniwaki, T Ueda, K Kita and H Shiku

Leukemia 17: 731-737; doi:10.1038/sj.leu.2402871

Molecular cytogenetic detection of chromosomal breakpoints in T-cell receptor gene loci FREE

S Gesk, J I Martín-Subero, L Harder, B Luhmann, B Schlegelberger, M J Calasanz, W Grote and R Siebert

Leukemia 17: 738-745; doi:10.1038/sj.leu.2402884

Apoptosis in CLL

Prodigiosin induces apoptosis of B and T cells from B-cell chronic lymphocytic leukemia FREE

C Campàs, M Dalmau, B Montaner, M Barragán, B Bellosillo, D Colomer, G Pons, R Pérez-Tomás and J Gil

Leukemia 17: 746-750; doi:10.1038/sj.leu.2402860

Upregulation of galectin-7 in murine lymphoma cells is associated with progression toward an aggressive phenotype FREE

S Moisan, M Demers, J Mercier, T Magnaldo, E F Potworowski and Y St-Pierre

Leukemia 17: 751-759; doi:10.1038/sj.leu.2402870

Improved engraftment of human acute myeloid leukemia progenitor cells in beta 2-microglobulin-deficient NOD/SCID mice and in NOD/SCID mice transgenic for human growth factors FREE

M Feuring-Buske, B Gerhard, J Cashman, R K Humphries, C J Eaves and D E Hogge

Leukemia 17: 760-763; doi:10.1038/sj.leu.2402882

The hepatocyte growth factor/Met pathway controls proliferation and apoptosis in multiple myeloma FREE

P W B Derksen, D J J de Gorter, H P Meijer, R J Bende, M van Dijk, H M Lokhorst, A C Bloem, M Spaargaren and S T Pals

Leukemia 17: 764-774; doi:10.1038/sj.leu.2402875

Myeloma

Thalidomide as initial therapy for early-stage myeloma FREE

S V Rajkumar, M A Gertz, M Q Lacy, A Dispenzieri, R Fonseca, S M Geyer, N Iturria, S Kumar, J A Lust, R A Kyle, P R Greipp and T E Witzig

Leukemia 17: 775-779; doi:10.1038/sj.leu.2402866

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Bio-Technical Methods Sections (BTS)

A flow cytometric method to detect apoptosis-related protein expression in minimal residual disease in acute myeloid leukemia  FREE

A van Stijn, A Kok, M A van der Pol, N Feller, G M J M Roemen, A H Westra, G J Ossenkoppele and G J Schuurhuis

Leukemia 17: 780-786; doi:10.1038/sj.leu.2402885

Appendix: Method In Focus

Multiparameter flow cytometric quantification of apoptosis-related protein expression FREE

A van Stijn, A Kok, M A van der Pol, N Feller, G M J M Roemen, A H Westra, G J Ossenkoppele and G J Schuurhuis

Leukemia 17: 787-788; doi:10.1038/sj.leu.2402886

Optimization of quantitative real-time RT-PCR parameters for the study of lymphoid malignancies FREE

I S Lossos, D K Czerwinski, M A Wechser and R Levy

Leukemia 17: 789-795; doi:10.1038/sj.leu.2402880

Appendix: Method In Focus

Optimization of quantitative real-time RT-PCR parameters for the study of lymphoid malignancies FREE

R Levy

Leukemia 17: 796-797; doi:10.1038/sj.leu.2402881

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Meeting Report

'Ponte di Legno' Working Group – Report on the Fifth International Childhood Acute Lymphoblastic Leukemia Workshop: Vienna, Austria, 29 April – 1 May 2002 FREE

H Gadner, O A Haas, G Masera, C-H Pui and M Schrappe

Leukemia 17: 798-803; doi:10.1038/sj.leu.2402872

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Spotlight Correspondence

Intramuscular edema as a complication of treatment with imatinib FREE

C Shimazaki, N Ochiai, R Uchida, S-I Fuchida, A Okano, E Ashihara, T Inaba, N Fujita and M Nakagawa

Leukemia 17: 804-805; doi:10.1038/sj.leu.2402868

G-CSF for Imatinib-induced neutropenia FREE

D Heim, M Ebnöther, S Meyer-Monard, D Tsakiris, M Linn, A Tichelli and A Gratwohl

Leukemia 17: 805-807; doi:10.1038/sj.leu.2402869

Simultaneous occurrence of a t(9;22) (Ph) with a t(2;11) in a patient with CML and emergence of a new clone with the t(2;11) alone after imatinib mesylate treatment FREE

B Royer-Pokora, B Hildebrandt, A Redmann, C Herold, R Kronenwett, R Haas, M Drechsler and C Wieland

Leukemia 17: 807-810; doi:10.1038/sj.leu.2402877

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Correspondence

Cost–effectiveness of repeated aphereses in poor mobilizers undergoing high-dose chemotherapy and autologous hematopoietic cell transplantation FREE

C Chabannon, A-G Le Corroller, F Viret, C Eillen, C Faucher, J-P Moatti, P Viens, N Vey, A-C Braud, G Novakovitch, P Ladaique, A-M Stoppa, J Camerlo, D Genre, D Maraninchi and D Blaise

Leukemia 17: 811-813; doi:10.1038/sj.leu.2402867

MYC is not overexpressed in a case of chronic myelomonocytic leukemia with MYC-containing double minutes FREE

K Paulsson, C Lassen, N Kuric, R Billström, T Fioretos, H J Tanke and B Johansson

Leukemia 17: 813-815; doi:10.1038/sj.leu.2402841

Reduced expression of H19 in bone marrow cells from chronic myeloproliferative disorders FREE

Oliver Bock, Jerome Schlué and Hans Kreipe

Leukemia 17: 815-816; doi:10.1038/sj.leu.2402830

Age-related changes of P-glycoprotein-mediated rhodamine 123 efflux in normal human bone marrow hematopoietic stem cells FREE

R T Calado, C G Machado, J J Carneiro, A B Garcia and R P Falcão

Leukemia 17: 816-818; doi:10.1038/sj.leu.2402853

FGF-2 expression and its action in human leukemia and lymphoma cell lines FREE

P Krejci, J Faitova, H Laurell, A Hampl and P Dvorak

Leukemia 17: 818-820; doi:10.1038/sj.leu.2402861

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