Volume 17 Issue 12, December 2003

Leading Article

• Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: Report of the BIOMED-2 Concerted Action BMH4-CT98-3936

  • J J M van Dongen
  • A W Langerak
  • E A Macintyre

  Leading Article 12 Dec 2003

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• Standardization and quality control studies of ‘real-time’ quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia – A Europe Against Cancer Program

  • J Gabert
  • E Beillard
  • J J M van Dongen

  Leading Article 09 Oct 2003

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Review

• Treatment by design in leukemia, a meeting report, Philadelphia, Pennsylvania, December 2002

  • R A Larson
  • G Q Daley
  • J A McCubrey

  Review 09 Oct 2003

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Commentary

• A further milestone towards comprehensive standardization of quantitative RT-PCR protocols for leukemic fusion gene transcripts has been reached

  • A Hochhaus

  Commentary 09 Oct 2003

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Keynote Address

• Unsolved issues in CLL biology and management

  • G Dighiero

  Keynote Address 02 Oct 2003

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Spotlight

• Dynamics of BCR-ABL mRNA expression in first-line therapy of chronic myelogenous leukemia patients with imatinib or interferon α/ara-C

  • M C Müller
  • N Gattermann
  • A Hochhaus

  Spotlight 02 Oct 2003

• Imatinib produces significantly superior molecular responses compared to interferon alfa plus cytarabine in patients with newly diagnosed chronic myeloid leukemia in chronic phase

  • S Branford
  • Z Rudzki
  • T P Hughes

  Spotlight 02 Oct 2003

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Molecular Targets For Therapy (MTT)

• Telomerase is limiting the growth of acute myeloid leukemia cells

  • A Röth
  • S Vercauteren
  • P M Lansdorp

  Molecular Targets For Therapy (MTT) 09 Oct 2003

• Increased expression of fibroblast growth factor receptor 3 in CD34+ BCR-ABL+ cells from patients with chronic myeloid leukemia

  • P Dvorak
  • D Dvorakova
  • J Mayer

  Molecular Targets For Therapy (MTT) 09 Oct 2003

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Original Manuscript

• ZAP-70 expression is a prognostic factor in chronic lymphocytic leukemia

  • J Dürig
  • H Nückel
  • U Dührsen

  Original Manuscript 02 Oct 2003

• Flavopiridol downregulates the expression of both the inducible NO synthase and p27^kip1 in malignant cells from B-cell chronic lymphocytic leukemia

  • C Billard
  • C Kern
  • J-P Kolb

  Original Manuscript 18 Sept 2003

• Marrow fibrosis, indicator of therapy failure in chronic myeloid leukemia – prospective long-term results from a randomized-controlled trial

  • G Buesche
  • R Hehlmann
  • A Georgii

  Original Manuscript 16 Oct 2003

• B-cell development in the presence of the MLL/AF4 oncoprotein proceeds in the absence of HOX A7 and HOX A9 expression

  • F E Bertrand
  • J D Spengeman
  • T W LeBien

  Original Manuscript 16 Oct 2003

• Expression of FLIP_Long and FLIP_Short in bone marrow mononuclear and CD34+ cells in patients with myelodysplastic syndrome: correlation with apoptosis

  • M Benesch
  • U Platzbecker
  • W Leisenring

  Original Manuscript 16 Oct 2003

• Synaptojanin 2 is recognized by HLA class II-restricted hairy cell leukemia-specific T cells

  • E H A Spaenij-Dekking
  • J Van Delft
  • J C Kluin-Nelemans

  Original Manuscript 16 Oct 2003

• Evaluation of candidate control genes for diagnosis and residual disease detection in leukemic patients using ‘real-time’ quantitative reverse-transcriptase polymerase chain reaction (RQ-PCR) – a Europe against cancer program

  • E Beillard
  • N Pallisgaard
  • J Gabert

  Original Manuscript 09 Oct 2003

• Somatic mitochondrial DNA mutations in adult-onset leukaemia

  • L He
  • L Luo
  • D M Turnbull

  Original Manuscript 02 Oct 2003

• Dual mutations in the AML1 and FLT3 genes are associated with leukemogenesis in acute myeloblastic leukemia of the M0 subtype

  • N Matsuno
  • M Osato
  • N Asou

  Original Manuscript 09 Oct 2003

• Stimulation of non-Hodgkin's lymphoma via HVEM: an alternate and safe way to increase Fas-induced apoptosis and improve tumor immunogenicity

  • R T Costello
  • F Mallet
  • D Olive

  Original Manuscript 16 Oct 2003

• Heterogeneous copy numbers of API2-MALT1 chimeric transcripts in mucosa-associated lymphoid tissue lymphoma

  • M Suguro-Katayama
  • R Suzuki
  • M Seto

  Original Manuscript 16 Oct 2003

• Increased serum levels of interleukin-9 correlate to negative prognostic factors in Hodgkin's lymphoma

  • M Fischer
  • M Bijman
  • G Nilsson

  Original Manuscript 09 Oct 2003

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Biotechnical Methods Section BTS

• Comparison between TaqMan and LightCycler technologies for quantification of minimal residual disease by using immunoglobulin and T-cell receptor genes consensus probes

  • C Eckert
  • C A Scrideli
  • G Cazzaniga

  Biotechnical Methods Section BTS 09 Oct 2003

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Spotlight Correspondence

• Autologous peripheral blood stem cell transplantation of stem cells harvested in imatinib-induced complete cytogenetic remission: an example of in vivo purging in CML

  • P le Coutre
  • K A Kreuzer
  • R Arnold

  Spotlight Correspondence 09 Oct 2003

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Correspondence

• Influence of stochastics on quantitative PCR in the detection of minimal residual disease

  • D Rawer
  • A Borkhardt
  • J Kreuder

  Correspondence 12 Dec 2003

• Response to Influence of stochastics on quantitative PCR in the detection of minimal residual disease by Rawer et al

  • R Arlinghaus
  • H Lin
  • J Q Guo

  Correspondence 12 Dec 2003

• Reply to Arlinghaus et al

  • D Rawer
  • A Borkhardt
  • J Kreuder

  Correspondence 12 Dec 2003

• Reply to Rawer et al (second letter)

  • R Arlinghaus
  • H Lin
  • S Ke

  Correspondence 12 Dec 2003

• Reply to Arlinghaus et al (second letter)

  • D Rawer
  • A Borkhardt
  • J Kreuder

  Correspondence 12 Dec 2003

• Reply to Hasle et al

  • A Gassas
  • M H Freedman
  • Y Dror

  Correspondence 02 Oct 2003

• Reply to Gassas et al

  • H Hasle
  • C M Niemeyer
  • D R Head

  Correspondence 02 Oct 2003

• Disruption of INK4/CDK/Rb cell cycle pathway by gene hypermethylation in multiple myeloma and MGUS

  • C S Chim
  • T K Fung
  • R Liang

  Correspondence 11 Sept 2003

• High incidence of trisomies 1q, 9q, and 11q in multiple myeloma: results from a comprehensive molecular cytogenetic analysis

  • P Liebisch
  • C Wendl
  • H Döhner

  Correspondence 02 Oct 2003

• EBV-related lymphoproliferative disorders in immunocompetent patients

  • M Oosterveld
  • W J Lesterhuis
  • J H J M van Krieken

  Correspondence 02 Oct 2003

• Unrelated umbilical cord blood stem cell transplant after failure of haploidentical or matched unrelated donor hematopoietic stem cell transplant

  • O Khorshid
  • E de Meis
  • M de Lima

  Correspondence 02 Oct 2003

• GST polymorphisms and occurrence of second neoplasms after treatment of childhood leukemia

  • J Jazbec
  • R Aplenc
  • B Jereb

  Correspondence 02 Oct 2003

• Successful treatment of hyperuricemia with low doses of recombinant urate oxidase in four patients with hematologic malignancy and tumor lysis syndrome

  • M Hummel
  • D Buchheidt
  • R Hehlmann

  Correspondence 02 Oct 2003

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